(S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone

Base Information

• Chemical Name: (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone
• CAS No.: 1236304-71-4
• Molecular Formula: C₁₅H₁₈O₃
• Molecular Weight: 246.306
• Mol file: 1236304-71-4.mol

Synonyms:(S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone

Chemical Property of (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone

There total 1 articles about (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(R)-2-(2-methoxymethoxy-4-methylphenyl)-2-methyl-4-oxopentanal (1236304-77-0) → (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone (1236304-71-4)

Guidance literature:

With potassium carbonate; In tert-butyl alcohol; at 20 ℃; for 10h; Reflux; Inert atmosphere;

DOI:10.1016/j.tet.2010.04.134

Reference yield:

1-Hydroxymethyl-1H-benzotriazole (28539-02-8) + (S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone (1236304-71-4) → C16H20O4

Guidance literature:

(S)-4-(2-methoxymethoxy-4-methylphenyl)-4-methyl-2-cyclopentenone; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

1-Hydroxymethyl-1H-benzotriazole; In tetrahydrofuran; methanol; hexane; at -78 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tet.2010.04.134

upstream raw materials:

(R)-2-(2-methoxymethoxy-4-methylphenyl)-2-methyl-4-oxopentanal