(αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid

Base Information

• Chemical Name: (αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid
• CAS No.: 135971-96-9
• Molecular Formula: C₂₁H₂₇N*ClH
• Molecular Weight: 329.913
• Mol file: 135971-96-9.mol

Synonyms:(αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid

Chemical Property of (αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid

There total 1 articles about (αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenylcycloheptanone (14996-78-2) + (S)-1-phenyl-ethylamine (2627-86-3) → (αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid (135971-96-9)

Guidance literature:

With hydrogen; titanium tetrachloride; nickel; Yield given. Multistep reaction; 1.) Et₂O, pentane, reflux, 2 h, 2.) EtOH, 5 bar, 35 deg C, 10 d;

DOI:10.1002/ardp.19913240604

Reference yield: 90.0%

(αS,1S,2S)-(-)-cis-2-Phenyl-N-(1-phenylethyl)cycloheptanamin-Hydrochlorid (135971-96-9) → (1S,2S)-(+)-cis-2-Phenylcycloheptanamin-Hydrochlorid (133577-20-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 50 ℃; for 48h; under 3750.3 Torr;

DOI:10.1002/ardp.19913240604

upstream raw materials:

2-phenylcycloheptanone

(S)-1-phenyl-ethylamine

Downstream raw materials:

(1S,2S)-(+)-cis-2-Phenylcycloheptanamin-Hydrochlorid