3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl

Base Information

• Chemical Name: 3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl
• CAS No.: 1422058-68-1
• Molecular Formula: C₁₇H₁₈NO₃
• Molecular Weight: 284.335
• Mol file: 1422058-68-1.mol

Synonyms:3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl

Chemical Property of 3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl

There total 1 articles about 3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,2,5,5-tetramethyl-4-phenylethynyl-2,5-dihydro-1H-pyrrole-3-carbaldehyde-1-yloxyl radical (505092-73-9) → 3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl (1422058-68-1)

Guidance literature:

2,2,5,5-tetramethyl-4-phenylethynyl-2,5-dihydro-1H-pyrrole-3-carbaldehyde-1-yloxyl radical; With sodium chlorite; potassium dihydrogenphosphate; dihydrogen peroxide; In water; acetonitrile; at 0 - 20 ℃; for 1.5h;

With hydrogenchloride; sodium disulfite; In water; acetonitrile;

DOI:10.1055/s-0032-1317516

Reference yield: 78.0%

3-carboxy-2,2,5,5-tetramethyl-4-(phenylethynyl)-2,5-dihydro-1H-pyrrol-1-oxyl (1422058-68-1) → 1,1,3,3-tetramethyl-4-oxo-6-phenyl-1,2,3,4-tetrahydropyrano[3,4-c]pyrrol-2-oxyl (1422058-69-2)

Guidance literature:

With gold(III) chloride; In acetonitrile; Reflux;

DOI:10.1055/s-0032-1317516

upstream raw materials:

2,2,5,5-tetramethyl-4-phenylethynyl-2,5-dihydro-1H-pyrrole-3-carbaldehyde-1-yloxyl radical

Downstream raw materials:

1,1,3,3-tetramethyl-4-oxo-6-phenyl-1,2,3,4-tetrahydropyrano[3,4-c]pyrrol-2-oxyl