[4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall

Base Information

• Chemical Name: [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall
• CAS No.: 828249-33-8
• Molecular Formula: C₁₁₄H₉₆O₁₆
• Molecular Weight: 1722.01
• Mol file: 828249-33-8.mol

Synonyms:[4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall

Chemical Property of [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall

There total 2 articles about [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

5,7,3',4'-tetra-O-benzyl-(+)-catechin (20728-73-8) + (2R,3S,4S)-5,7,3',4'-tetra-O-benzyl-4-(2''-ethoxyethoxy)flavan-3-yl (3'',4'',5''-tri-O-benzyl)gallate (828249-32-7) → [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall (828249-33-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -20 ℃; for 0.0833333h;

DOI:10.1016/j.tet.2004.10.048

Reference yield: 26.0%

3,4,5-tribenzyloxybenzoic acid (1486-48-2) + 5,7,3',4'-tetra-O-benzyl-4α-(5,7,3',4'-tetra-O-benzylcatechin)catechin (137550-06-2) → [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3”-(tribenzyloxy)gallate + [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall (828249-33-8) + [4,8’]-2,3-trans-3.4-trans:2’,3’-trans-Octabenzyloxy-bi-(+)-catechin-3,3”-di-(tribenzyloxy)gallate (223387-33-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.3987/COM-05-S(T)11

Reference yield: 100.0%

[4,8’]-2,3-trans-3.4-trans:2’,3’-trans-octabenzyloxy-(+)-catechin-3-(tribenzyloxy)gall (828249-33-8) → gallocatechin-(4α->8)-catechin

Guidance literature:

With hydrogen; palladium(II) hydroxide; In tetrahydrofuran; methanol; water; for 24h;

DOI:10.1016/j.bmcl.2013.06.061

upstream raw materials:

5,7,3',4'-tetra-O-benzyl-(+)-catechin

(2R,3S,4S)-5,7,3',4'-tetra-O-benzyl-4-(2''-ethoxyethoxy)flavan-3-yl (3'',4'',5''-tri-O-benzyl)gallate

3,4,5-tribenzyloxybenzoic acid

5,7,3',4'-tetra-O-benzyl-4α-(5,7,3',4'-tetra-O-benzylcatechin)catechin