(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Base Information

Chemical Name:(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate
CAS No.:100165-56-8
Molecular Formula:C₂₂H₃₂N₂O₅
Molecular Weight:404.506
Hs Code.:

Synonyms:(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Suppliers and Price of (2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

There total 2 articles about (2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 27687-12-3
(1r,4r)-4-({[(benzyloxy)carbonyl]amino}methyl)cyclohexane-1-carboxylic acid

: 66297-46-9
N-hydroxymethyl trimethylacetamide

: 100165-56-8
(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 48h; Ambient temperature;
DOI:10.1021/jm00154a004

Reference yield:

: 754-10-9
2,2-dimethylpropionamide

: 100165-56-8
(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / K₂CO₃ / H₂O / 40 °C

2: 83 percent / dicyclohexylcarbodiimide, 4-(N,N-dimethylamino)pyridine / CH₂Cl₂ / 48 h / Ambient temperature

With dmap; potassium carbonate; dicyclohexyl-carbodiimide; In dichloromethane; water;
DOI:10.1021/jm00154a004

Reference yield:

: 100165-56-8
(2,2-dimethylpropanamido)methyl trans-4-<<<(benzyloxy)carbonyl>amino>methyl>cyclohexanecarboxylate

: 4-Aminomethyl-cyclohexanecarboxylic acid (2,2-dimethyl-propionylamino)-methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In isopropyl alcohol; at 22 ℃; for 3h; under 750.06 Torr;
DOI:10.1021/jm00154a004