D-Valinol

Base Information Edit

Chemical Name:D-Valinol
CAS No.:4276-09-9
Molecular Formula:C5H13NO
Molecular Weight:103.164
Hs Code.:29051990
European Community (EC) Number:922-908-4,628-067-7
UNII:829QNS6ERZ
DSSTox Substance ID:DTXSID80426204
Nikkaji Number:J63.546D
Wikidata:Q72439275
Mol file:4276-09-9.mol

Synonyms:D-Valinol;4276-09-9;(R)-(-)-2-Amino-3-methyl-1-butanol;(2R)-2-amino-3-methylbutan-1-ol;(R)-2-Amino-3-methylbutan-1-ol;(R)-2-Amino-3-methyl-1-butanol;(R)-valinol;(R)-2-Amino-3-methyl-butan-1-ol;MFCD00064297;(2R)-2-amino-3-methyl-1-butanol;1-Butanol, 2-amino-3-methyl-, (R)-;H-D-Val-ol;D-2-Amino-3-methyl-1-butanol;Valinol, D-;(-)-Valinol;(1R)-1-Isopropyl-2-hydroxyethylamine;(R)-(-)-valinol;829QNS6ERZ;SCHEMBL82571;2-Amino-3-methyl-1-butanol #;DTXSID80426204;(-)-2-amino-3-methyl-1-butanol;CS-D0610;BBL101600;STL555396;1-Butanol, 2-amino-3-methyl-, D-;AKOS005259795;AC-13953;AS-12364;HY-30167;(R)-(-)-2-amino-3-methyl-butan-1-ol;1-Butanol, 2-amino-3-methyl-, (2R)-;AM20100129;V0077;[(R)-1-(Hydroxymethyl)-2-methylpropyl]amine;EN300-98065;(R)-(-)-2-Amino-3-methyl-1-butanol, 98%;A826002;Q-102724;Q-200023;D-Valinol, purum, >=96.0% (sum of enantiomers, GC);(2R)-2-amino-3-methyl-butan-1-ol

Suppliers and Price of D-Valinol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-Valinol
1g
$ 156.00

TRC
D-Valinol
5g
$ 80.00

TCI Chemical
D-Valinol >98.0%(GC)(T)
5g
$ 116.00

TCI Chemical
D-Valinol >98.0%(GC)(T)
1g
$ 40.00

SynQuest Laboratories
(R)-(-)-2-Amino-3-methylbutan-1-ol
25 g
$ 77.00

Sigma-Aldrich
(R)-(?)-2-Amino-3-methyl-1-butanol 98%
5g
$ 178.00

Sigma-Aldrich
(R)-(?)-2-Amino-3-methyl-1-butanol 98%
1g
$ 68.60

Oakwood
D-Valinol 98%
5g
$ 14.00

Medical Isotopes, Inc.
D-Valinol
5 mg
$ 790.00

Medical Isotopes, Inc.
D-Valinol
50 mg
$ 1000.00

Total 118 raw suppliers

Chemical Property of D-Valinol Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Melting Point:35-36 °C(lit.)
Refractive Index:1.455
Boiling Point:186.8 °C at 760 mmHg
PKA:12.82±0.10(Predicted)
Flash Point:91.1 °C
PSA：46.25000
Density:0.912 g/cm³
LogP:0.66230
Storage Temp.:2-8°C
Sensitive.:Air Sensitive
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:103.099714038
Heavy Atom Count:7
Complexity:45.3

Purity/Quality:

99% ^*data from raw suppliers

D-Valinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37-36-36/37/38

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(CO)N
Isomeric SMILES:CC(C)[C@H](CO)N
Uses D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease.

Technology Process of D-Valinol

There total 14 articles about D-Valinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%