5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole

Base Information

• Chemical Name: 5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole
• CAS No.: 143945-72-6
• Molecular Formula: C26H19BrN4
• Molecular Weight: 467.368
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID50443605
• Wikidata: Q72511449
• Mol file: 143945-72-6.mol

Synonyms:5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole;143945-72-6;5-(2-bromophenyl)-1-trityltetrazole;C26H19BrN4;n-(triphenylmethyl)-5-(2-bromophenyl)-1h-tetrazole;SCHEMBL2447241;DTXSID50443605;KHMJZQFKDOBODS-UHFFFAOYSA-N;5-(2-bromophenyl)-1-(triphenylmethyl)-1H-1,2,3,4-tetrazole;AKOS015835236;5-(2-bromophenyl)-1-trityl-1H-tetrazole;FT-0648917;Propanal, 3,3,3-trifluoro-2-oxo-, 1-oxime;10.14272/KHMJZQFKDOBODS-UHFFFAOYSA-N.1;5-(2-Bromophenyl)-1-triphenylmethyl-1H-tetrazole;A808142;doi:10.14272/KHMJZQFKDOBODS-UHFFFAOYSA-N.1

Chemical Property of 5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.668
• Boiling Point: 623.249 °C at 760 mmHg
• PKA: 0.16±0.10(Predicted)
• Flash Point: 330.729 °C
• PSA: 43.60000
• Density: 1.331 g/cm³
• LogP: 5.94280
• XLogP3: 6.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 466.07931
• Heavy Atom Count: 31
• Complexity: 508

Purity/Quality:

99% ^*data from raw suppliers

5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N4C(=NN=N4)C5=CC=CC=C5Br

Technology Process of 5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole

There total 3 articles about 5-(2-Bromophenyl)-1-(triphenylmethyl)-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-(2-bromophenyl)-1H-tetrazole (73096-42-1) + trityl chloride (76-83-5) → N-trityl-5-(2-bromophenyl)tetrazole (143945-72-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 40 ℃; for 1h;

Reference yield:

trityl chloride (76-83-5) → N-trityl-5-(2-bromophenyl)tetrazole (143945-72-6)

Guidance literature:

With triethylamine; In dichloromethane;

Reference yield:

1,4-dioxane (123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6) + trityl chloride (76-83-5) → N-trityl-5-(2-bromophenyl)tetrazole (143945-72-6)

Guidance literature:

In dichloromethane;

upstream raw materials:

5-(2-bromophenyl)-1H-tetrazole

trityl chloride

1,4-dioxane

Downstream raw materials:

N-[(2'-(1-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl)methyl]-N-valeroyl-(L)-valine benzyl ester

N-[[2'-(1-triphenylmethyltetrazol-5yl)biphenyl-4-yl]methyl]-N-valeryl-L-valine methyl ester

tert-butyl N-pentanoyl-N-[{2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl]-1,1'-biphenyl-4-yl}methyl]-L-valinate

trityl irbesartan

Refernces

• 1、 -. "METHOD FOR THE PRODUCTION OF LOSARTAN". Page/Page column 20; 33-34. . Retrieved 2008/06/13.
• 2、 -. "N-ARYLHETEROARYLALKYL IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS". . . Retrieved 2008/06/13.