(1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate

Base Information

Chemical Name:(1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate
CAS No.:1352832-29-1
Molecular Formula:C₂₂H₂₃F₆N₂O₄PS
Molecular Weight:556.466
Hs Code.:

Synonyms:(1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate

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Chemical Property of (1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate

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Technology Process of (1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate

There total 1 articles about (1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 871828-95-4
1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)thiourea

: 814-49-3
diethyl chlorophosphate

: 1352832-29-1
(1R,2S)-1-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-2,3-dihydro-1H-inden-2-yl diethyl phosphate

Guidance literature:: 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)thiourea; With 1-methyl-1H-imidazole; In dichloromethane; at 0 ℃; for 0.333333h; Inert atmosphere;

diethyl chlorophosphate; In dichloromethane; at 0 - 20 ℃; for 2.25h;
DOI:10.1002/chem.201102793