2-Amino-4-chloro-5-formylthiophene-3-carbonitrile

Base Information

Chemical Name:2-Amino-4-chloro-5-formylthiophene-3-carbonitrile
CAS No.:104366-23-6
Molecular Formula:C6H3ClN2OS
Molecular Weight:186.622
Hs Code.:29349990
European Community (EC) Number:622-475-9
DSSTox Substance ID:DTXSID70372180
Nikkaji Number:J472.980C
Wikidata:Q72435056
Mol file:104366-23-6.mol

Synonyms:104366-23-6;2-amino-4-chloro-5-formylthiophene-3-carbonitrile;2-Amino-4-chloro-3-cyano-5-formylthiophene;2-Amino-3-cyano-4-chloro-5-formylthiophene;2-amino-4-chloro-5-formyl-3-thiophenecarbonitrile;3-Thiophenecarbonitrile, 2-amino-4-chloro-5-formyl-;MFCD03788265;2-Amino-3-cyano-4-chlorothiophene-5-carboxaldehyde;SCHEMBL909857;DTXSID70372180;XIZSUYSWKGAOCN-UHFFFAOYSA-N;AKOS015854766;SB66981;AC-28065;AS-11845;SY025188;FT-0649674;A800964;J-507838;2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile, 90%;2-amino-4-chloro-5-formyl-thiophene-3-carbonitrile;2-Amino-4-chloro-5-formylthiophene-3-carbonitrile

Suppliers and Price of 2-Amino-4-chloro-5-formylthiophene-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4-chloro-5-formylthiophene-3-carbonitrile
100mg
$ 60.00

TCI Chemical
2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile >98.0%(GC)
1g
$ 72.00

TCI Chemical
2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile >98.0%(GC)
5g
$ 216.00

Sigma-Aldrich
2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile 90%
1g
$ 125.00

Matrix Scientific
2-Amino-4-chloro-5-formylthiophene-3-carbonitrile 97%
1g
$ 249.00

Labseeker
2-AMINO-3-CYANO-4-CHLORO-5-FORMYLTHIOPHENE 95
250g
$ 3500.00

Crysdot
2-Amino-4-chloro-3-cyano-5-formylthiophene 95+%
25g
$ 333.00

Chem-Impex
2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile,≥98%(GC)Hazmat ≥98%(GC)
5G
$ 261.83

Chemenu
2-Amino-4-chloro-5-formylthiophene-3-carbonitrile 95%
25g
$ 311.00

Biosynth Carbosynth
2-Amino-3-cyano-4-chloro-5-formylthiophene
10 g
$ 659.00

Total 56 raw suppliers

Chemical Property of 2-Amino-4-chloro-5-formylthiophene-3-carbonitrile

Chemical Property:

Vapor Pressure:1.48E-05mmHg at 25°C
Melting Point:270-271°C
Refractive Index:1.646
Boiling Point:366.3 °C at 760 mmHg
PKA:-4.06±0.10(Predicted)
Flash Point:175.3 °C
PSA：95.12000
Density:1.58 g/cm³
LogP:2.24908
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:185.9654616
Heavy Atom Count:11
Complexity:214

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-4-chloro-5-formylthiophene-3-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,C
Statements: 22-34-43
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(=O)C1=C(C(=C(S1)N)C#N)Cl

Technology Process of 2-Amino-4-chloro-5-formylthiophene-3-carbonitrile

There total 2 articles about 2-Amino-4-chloro-5-formylthiophene-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 104366-23-6
2-amino-4-chloro-5-formyl-3-cyanothiophene

Guidance literature:

Reference yield:

: N,N-dimethyl-N'-(4-chloro-3-cyano-5-formylthien-2-yl)-formamidine

: 104366-23-6
2-amino-4-chloro-5-formyl-3-cyanothiophene

Guidance literature:: With formic acid; In water;

Reference yield: 86.0%

: 104366-23-6
2-amino-4-chloro-5-formyl-3-cyanothiophene

: 1-Benzyl-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile

: C₂₀H₁₂ClN₅O₃S

Guidance literature:: 2-amino-4-chloro-5-formyl-3-cyanothiophene; With phosphoric acid; sulfuric acid; sodium nitrite; at -5 ℃; for 0.5h;

1-Benzyl-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile; In methanol; water; at 0 - 5 ℃; for 1h;
DOI:10.1016/j.dyepig.2017.04.046