Pantoloc

Base Information Edit

Chemical Name:Pantoloc
CAS No.:138786-67-1
Molecular Formula:C16H15F2N3NaO4S
Molecular Weight:405.357
Hs Code.:2933990090
European Community (EC) Number:604-093-4
Mol file:138786-67-1.mol

Synonyms:Controloc;Pantoloc;Protonix;Protonix IV;Protonix I.V.;Pantoprazole Sodium [USAN];C16H15F2N3O4S.Na;1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1);5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methane]sulfinyl}-1-sodio-1H-1,3-benzodiazole;C16-H15-F2-N3-O4-S.Na;5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole sodium;SCHEMBL3542;WHCXDEORRDVLKS-UHFFFAOYSA-N;AKOS015888692;AKOS037643304;AS-13270

Suppliers and Price of Pantoloc

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Pantoprazole, Sodium Salt
100mg
$ 403.00

TRC
PantoprazoleSodiumSalt
1g
$ 970.00

Sigma-Aldrich
Pantoprazole Sodium Pharmaceutical Secondary Standard; Certified Reference Material
1 g
$ 78.20

Sigma-Aldrich
Pantoprazole sodium United States Pharmacopeia (USP) Reference Standard
250 mg
$ 366.00

Medical Isotopes, Inc.
Pantoprazolesodiumsalt
250 mg
$ 590.00

Medical Isotopes, Inc.
Pantoprazolesodiumsalt
50 mg
$ 190.00

Matrix Scientific
5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl) sulfinyl)-1H-benzimidazole sodium
0.500g
$ 160.00

Matrix Scientific
5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl) sulfinyl)-1H-benzimidazole sodium
1g
$ 200.00

Labseeker
Pantoprazole Sodium 98
1kg
$ 769.00

DC Chemicals
Pantoprazole Sodium >98%
1 g
$ 300.00

Total 225 raw suppliers

Chemical Property of Pantoloc Edit

Chemical Property:

Appearance/Colour:white to off-white solid
Melting Point:199-202 °C
Boiling Point:586.9oC at 760 mmHg
Flash Point:308.7oC
PSA：94.68000
LogP:3.53580
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:7
Exact Mass:406.06490275
Heavy Atom Count:27
Complexity:490

Purity/Quality:

99% ^*data from raw suppliers

Pantoprazole, Sodium Salt ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-37/38-41-48
Safety Statements: 22-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC.[Na]
Recent ClinicalTrials:Investigate a Pharmacokinetics Between S-pantoprazole 20mg and Pantoprazole 40mg in Healthy Male Subjects
Recent EU Clinical Trials:F?rekomst av syrarelaterade besv?r efter uts?ttning av protonpumpsh?mmare hos friska frivilliga.
Uses An antiulcerative. Gastric pump inhibitor. An antiulcerative. Gastric pump inhibitor Gastrointestinal
Therapeutic Function Antiulcer

Technology Process of Pantoloc

There total 13 articles about Pantoloc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 138786-67-1
pantoprazole sodium

Guidance literature:: Purification / work up;

Reference yield: 95.0%

: 102625-70-7
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole

: 138786-67-1
pantoprazole sodium

Guidance literature:: With sodium hydroxide; In water; acetonitrile; at 20 ℃;

Reference yield: 95.0%

: 102625-64-9
pantoprazole sulfide

: 138786-67-1
pantoprazole sodium

Guidance literature:: pantoprazole sulfide; With sodium hydroxide; tert-butylhypochlorite; In dichloromethane; water; at 0 - 5 ℃; for 1h;

With sodium hydroxide; In water; acetone; at 0 - 25 ℃; for 7h;