4-Amino-3-bromo-5-cyano-salicylsaeure

Base Information

• Chemical Name: 4-Amino-3-bromo-5-cyano-salicylsaeure
• CAS No.: 102569-25-5
• Molecular Formula: C₈H₅BrN₂O₃
• Molecular Weight: 257.043
• Mol file: 102569-25-5.mol

Synonyms:4-Amino-3-bromo-5-cyano-salicylsaeure

Chemical Property of 4-Amino-3-bromo-5-cyano-salicylsaeure

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-Amino-3-bromo-5-cyano-salicylsaeure

There total 1 articles about 4-Amino-3-bromo-5-cyano-salicylsaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-Amino-5-cyano-salicylsaeure (72817-93-7) → 4-Amino-3-bromo-5-cyano-salicylsaeure (102569-25-5)

Guidance literature:

With bromine; In acetic acid; for 2.5h; Ambient temperature;

DOI:10.1055/s-1985-31345

Reference yield: 72.0%

4-Amino-3-bromo-5-cyano-salicylsaeure (102569-25-5) → 2-Amino-3-bromo-4-hydroxy-benzonitrile (102569-28-8)

Guidance literature:

In quinoline; at 170 - 180 ℃; for 0.75h;

DOI:10.1055/s-1985-31345

Reference yield:

4-Amino-3-bromo-5-cyano-salicylsaeure (102569-25-5) → 2-Amino-3,5-dibromo-4-hydroxybenzonitril (102569-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / quinoline / 0.75 h / 170 - 180 °C

2: bromine / acetic acid / 2.5 h / Ambient temperature

With bromine; In quinoline; acetic acid;

DOI:10.1055/s-1985-31345

upstream raw materials:

4-Amino-5-cyano-salicylsaeure

Downstream raw materials:

2-Amino-3-bromo-4-hydroxy-benzonitrile

2-Amino-3,5-dibromo-4-hydroxybenzonitril

2-Amino-3-bromo-4-hydroxy-5-iodo-benzonitrile