N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Base Information

Chemical Name:N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide
CAS No.:165055-11-8
Molecular Formula:C₃₁H₃₅N₃O₆
Molecular Weight:545.635
Hs Code.:

Synonyms:N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Suppliers and Price of N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

There total 3 articles about N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 2627-86-3
(S)-1-phenyl-ethylamine

: 96188-33-9
N-(carbobenzyloxy)-β-benzyl-L-aspartyl-D-α-aminobutyric acid

: 165055-11-8
N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Guidance literature:: With N-hydroxy-5-norbornene-2,3-dicarboximide; dicyclohexyl-carbodiimide; In 1,4-dioxane; Ambient temperature;
DOI:10.1021/jf00056a003

Reference yield:

: 3479-47-8
Z-Asp(OBzl)-OH

: 165055-11-8
N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Guidance literature:: Multi-step reaction with 3 steps

1: dicyclohexylcarbodiimide / tetrahydrofuran / Ambient temperature

2: 57 percent / Et₃N / dioxane; H₂O / Ambient temperature

3: 56 percent / dicyclohexylcarbodiimide, N-hydroxy-5-norbornene-2,3-dicarboximide / dioxane / Ambient temperature

With N-hydroxy-5-norbornene-2,3-dicarboximide; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/jf00056a003

Reference yield:

: 61464-33-3
O^γ-benzyl-N^α-benzyloxycarbonylaspartic acid succinimidyl ester

: 165055-11-8
N-CBZ-β-benzyl-L-aspartyl-D-α-aminobutyric acid (S)-α-methylbenzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / Et₃N / dioxane; H₂O / Ambient temperature

2: 56 percent / dicyclohexylcarbodiimide, N-hydroxy-5-norbornene-2,3-dicarboximide / dioxane / Ambient temperature

With N-hydroxy-5-norbornene-2,3-dicarboximide; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; water;
DOI:10.1021/jf00056a003