Technology Process of N-(4-methoxybenzenesulfonyl)-3-methyl-1-pentylfuro[3,4-b]indole
There total 6 articles about N-(4-methoxybenzenesulfonyl)-3-methyl-1-pentylfuro[3,4-b]indole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Amberlyst-15 acid ion-exchange resin;
In
water; isopropyl alcohol;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.tet.2011.10.022
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: aluminum (III) chloride / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere; Cooling with ice
3.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Reflux
4.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere
4.2: 20 °C / Inert atmosphere
4.3: Inert atmosphere
5.1: Amberlyst-15 acid ion-exchange resin / water; isopropyl alcohol / 2 h / 20 °C / Inert atmosphere
With
aluminum (III) chloride; sodium hydride; toluene-4-sulfonic acid; lithium diisopropyl amide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; isopropyl alcohol; toluene;
DOI:10.1016/j.tet.2011.10.022
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: Amberlyst-15 acid ion-exchange resin / water; isopropyl alcohol / 2 h / 20 °C / Inert atmosphere
With
lithium diisopropyl amide;
In
tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1016/j.tet.2011.10.022
