Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

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Chemical Name:Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide
CAS No.:913982-20-4
Molecular Formula:C₂₁H₃₁N₅O₂S
Molecular Weight:417.575
Hs Code.:

Synonyms:Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

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Chemical Property of Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

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Technology Process of Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

There total 3 articles about Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: (S)-1-cyclohexyl-1-methylprop-2-ynylamine hydrochloride

: 88-13-1
3-Thiophene carboxylic acid

: (R)-2-azidohexanoic acid

: 913982-20-4
Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

Guidance literature:: Multistep reaction;
DOI:10.1021/jm060701s

Reference yield:

: 913981-91-6
(Ss,S)-N-(1-cyclohexyl-1-methylprop-2-ynyl)-2-methylpropanesulfinamide

: 913982-20-4
Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / HCl / methanol; dioxane / 20 °C

With hydrogenchloride; In 1,4-dioxane; methanol;
DOI:10.1021/jm060701s

Reference yield:

: 910910-13-3
(S_S,S)-(+)-N-(1-cyclohexyl-1-methyl-3-(trimethylsilanyl)-prop-2-ynyl)-2-methyl-2-propanesulfinamide

: 913982-20-4
Thiophene-3-carboxylic acid {(S)-1-[1-((S)-1-carbamoyl-pentyl)-1H-[1,2,3]triazol-4-yl]-1-cyclohexyl-ethyl}-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / tetrabutylammonium fluoride / tetrahydrofuran / 20 °C

2: 99 percent / HCl / methanol; dioxane / 20 °C

With hydrogenchloride; tetrabutyl ammonium fluoride; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.1021/jm060701s