1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate

Base Information

Chemical Name:1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate
CAS No.:1312185-02-6
Molecular Formula:C₂HF₃O₂*C₂₅H₂₈Cl₂N₆O
Molecular Weight:613.467
Hs Code.:

Synonyms:1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate

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Chemical Property of 1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate

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Technology Process of 1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate

There total 1 articles about 1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 1176772-58-9
1-(4-amino-5-bromo-2-pyrimidinyl)-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide

: 28611-39-4
4-(dimethylamino)benzene-boronic acid

: 76-05-1
trifluoroacetic acid

: 1312185-02-6
1-{4-amino-5-[4-(dimethylamino)phenyl]-2-pyrimidinyl}-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide trifluoroacetate

Guidance literature:: 1-(4-amino-5-bromo-2-pyrimidinyl)-N-[(2,4-dichlorophenyl)methyl]-4-piperidinecarboxamide; 4-(dimethylamino)benzene-boronic acid; With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 160 ℃; for 0.1h; Inert atmosphere;

trifluoroacetic acid; In water; N,N-dimethyl-formamide;