(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

Base Information

Chemical Name:(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide
CAS No.:1259080-27-7
Molecular Formula:C₂₀H₂₅NOS
Molecular Weight:327.491
Hs Code.:

Synonyms:(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

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Technology Process of (R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

There total 3 articles about (R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 196929-85-8
(R)-N-benzylidene-2-methylpropane-2-sulfinamide

: 103-54-8
cinnamyl acetate

: 1259080-27-7
(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

: (R)-N-((1S,2S)-1,2-diphenylbut-3-en-1-yl)-2-methylpropane-2-sulfinamide

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; diethylzinc; In tetrahydrofuran; for 12h; diastereoselective reaction; Inert atmosphere; Schlenk technique; Enzymatic reaction;
DOI:10.1039/c7cc00108h

Reference yield: 96.0%

: 196929-85-8
(R)-N-benzylidene-2-methylpropane-2-sulfinamide

: 4392-24-9
Cinnamyl bromide

: 1259080-27-7
(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

Guidance literature:: With lithium chloride; zinc; In N,N-dimethyl-formamide; at 20 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c0cc03230a

Reference yield: 92.0%

: 196929-85-8
(R)-N-benzylidene-2-methylpropane-2-sulfinamide

: 4392-24-9,26146-77-0,115117-88-9
(Z)-cinnamyl bromide

: 1259080-27-7
(R)-N-((1R,2R)-2-(4-bromophenyl)-1-phenylbut-3-enyl)-2-methylpropane-2-sulfinamide

Guidance literature:: With lithium chloride; zinc; In N,N-dimethyl-formamide; at 20 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c0cc03230a