2-(Trifluoromethoxy)phenylboronic acid

Base Information

Chemical Name:2-(Trifluoromethoxy)phenylboronic acid
CAS No.:175676-65-0
Molecular Formula:C7H6BF3O3
Molecular Weight:205.929
Hs Code.:29163990
European Community (EC) Number:642-456-9
DSSTox Substance ID:DTXSID60380411
Nikkaji Number:J1.490.431J
Wikidata:Q72510706
Mol file:175676-65-0.mol

Synonyms:175676-65-0;2-(Trifluoromethoxy)phenylboronic acid;2-Trifluoromethoxyphenylboronic acid;2-(Trifluormethoxy)phenylboronic acid;2-(Trifluoromethoxy)benzeneboronic Acid;[2-(trifluoromethoxy)phenyl]boronic Acid;(2-(trifluoromethoxy)phenyl)boronic acid;MFCD01320763;Boronic acid, [2-(trifluoromethoxy)phenyl]-;2-Trifluormethoxyphenylboronic acid;SCHEMBL264406;DTXSID60380411;2-Trifluoromethoxyphenylboronicacid;2-Trifluoromethoxvphenylboronic acid;2-trifluromethoxyphenyl boronic acid;2-trifluoromethoxybenzeneboronic acid;2-trifluoromethoxyphenyl boronic acid;BBL100497;STL554291;2-(Trifluoromethoxy)phenylboranic acid;2-trifluoromethoxy-phenyl-boronic acid;AKOS004119240;2-trifluoromethoxy benzene boronic acid;AB09004;AC-6987;CS-W020020;2-(Trifluoromethoxy)-phenylboronic acid;2-(trifluoromethoxy)phenyl boronic acid;2-(trifluoromethoxy)phenyl-boronic acid;(2-trifluoromethoxy-phenyl)-boronic acid;AS-12130;BP-10157;SY013469;A3901;AM20060164;FT-0601800;T2413;EN300-49258;Boronic acid, B-[2-(trifluoromethoxy)phenyl]-;J-510351;Z330829074;(3-BOC-AMINO-PYRROLIDIN-1-YL)-PYRIDIN-3-YL-ACETICACID;2-(trifluoromethoxy)phenylboronic acid

Suppliers and Price of 2-(Trifluoromethoxy)phenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethoxy)phenylboronic acid
100g
$ 1090.00

TCI Chemical
2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)
1g
$ 17.00

TCI Chemical
2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)
5g
$ 51.00

Synthonix
2-(Trifluoromethoxy)phenylboronic acid 98%
5g
$ 70.00

Synthonix
2-(Trifluoromethoxy)phenylboronic acid 98%
1g
$ 25.00

SynQuest Laboratories
2-(Trifluoromethoxy)benzeneboronic acid 98%
25 g
$ 125.00

SynQuest Laboratories
2-(Trifluoromethoxy)benzeneboronic acid 98%
100 g
$ 375.00

SynQuest Laboratories
2-(Trifluoromethoxy)benzeneboronic acid 98%
5 g
$ 45.00

Sigma-Aldrich
2-(Trifluoromethoxy)phenylboronic acid
5g
$ 51.70

Sigma-Aldrich
2-(Trifluoromethoxy)phenylboronic acid
1g
$ 36.00

Total 92 raw suppliers

Chemical Property of 2-(Trifluoromethoxy)phenylboronic acid

Chemical Property:

Vapor Pressure:0.00411mmHg at 25°C
Melting Point:118-120 °C
Refractive Index:1.461
Boiling Point:267.2 °C at 760 mmHg
PKA:8.14±0.53(Predicted)
Flash Point:115.4 °C
PSA：49.69000
Density:1.41 g/cm³
LogP:0.26500
Storage Temp.:Keep Cold
Solubility.:soluble in Methanol
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:206.0362087
Heavy Atom Count:14
Complexity:186

Purity/Quality:

99% ^*data from raw suppliers

2-(Trifluoromethoxy)phenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22-22
Safety Statements: 26-36/37/39-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=CC=C1OC(F)(F)F)(O)O
Uses 2-(Trifluoromethoxy)phenylboronic Acid is a reagent that is used for the preparation of ERβ receptor that is selective towards 4-hydroxybiphenyls. suzuki reaction

Technology Process of 2-(Trifluoromethoxy)phenylboronic acid

There total 6 articles about 2-(Trifluoromethoxy)phenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 456-55-3
1-trifluoromethoxybenzene

: 175676-65-0
2-trifluoromethoxyphenylboronic acid

Guidance literature:: 1-trifluoromethoxybenzene; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -75 ℃; for 2h;

With fluorodimethoxyborane diethyl etherate; In tetrahydrofuran; cyclohexane; at -75 ℃;

With water; In tetrahydrofuran; cyclohexane; for 0.5h; Further stages.;
DOI:10.1002/1099-0690(200102)2001:4<691::AID-EJOC691>3.0.CO;2-A

Reference yield: 65.0%

: 64115-88-4
1-bromo-2-(trifluoromethoxy)benzene

: 175676-65-0
2-trifluoromethoxyphenylboronic acid

Guidance literature:: 1-bromo-2-(trifluoromethoxy)benzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.75h;

With Triisopropyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 16h;

With hydrogenchloride; sodium hydroxide; water; more than 3 stages;