Furan-3-boronic acid

Base Information

• Chemical Name: Furan-3-boronic acid
• CAS No.: 55552-70-0
• Molecular Formula: C4H5BO3
• Molecular Weight: 111.893
• Hs Code.: 29349990
• European Community (EC) Number: 672-302-6
• DSSTox Substance ID: DTXSID30370248
• Nikkaji Number: J1.357.418I
• Wikidata: Q72479616
• Mol file: 55552-70-0.mol

Synonyms:Furan-3-boronic acid;55552-70-0;3-Furanboronic acid;furan-3-ylboronic acid;3-furylboronic Acid;3-Furanylboronic Acid;(furan-3-yl)boronic acid;MFCD01319007;Boronic acid, 3-furanyl-;furan-3-yl-boronic acid;3-Furanboronicacid;FURAN-3-YL-3-BORONIC ACID;3-furaneboronic acid;3-furan boronic acid;3-furyl boronic acid;3-furane boronic acid;3-furanyl boronic acid;furan -3-boronic acid;furan-3-yl boronic acid;SCHEMBL42461;DTXSID30370248;CYEFKCRAAGLNHW-UHFFFAOYSA-N;BCP18405;3-Furanylboronic acid, >=95.0%;AKOS009158919;AB08822;CS-W001222;GS-6852;NCGC00249550-01;SY001064;A8031;AM20100363;F0438;FT-0601790;Furan-3-boronicacid;FURAN-3-BORONIC ACID;EN300-87221;J-521400;F0001-1458;Z1179935144

Chemical Property of Furan-3-boronic acid

Chemical Property:

• Appearance/Colour: White to light yellow crystal powder
• Vapor Pressure: 0.0134mmHg at 25°C
• Melting Point: 139-144 °C (dec.)(lit.)
• Refractive Index: 1.49
• Boiling Point: 247.7 °C at 760 mmHg
• PKA: 7.95±0.10(Predicted)
• Flash Point: 103.6 °C
• PSA: 53.60000
• Density: 1.25 g/cm³
• LogP: -1.04060
• Storage Temp.: 0-6°C
• Solubility.: Soluble in methanol.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 112.0331742
• Heavy Atom Count: 8
• Complexity: 75.7

Purity/Quality:

99% ^*data from raw suppliers

Furan-3-boronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-3-37

MSDS Files:

Useful:

• Canonical SMILES: B(C1=COC=C1)(O)O
• Uses: Furan-3-boronic acid use furan-3-boronic acid as our coupling partner in many reactions. A chitosan uricase (UOx)-poly (furan-3-boronic acid)(PFBA)-Pd nanoparticles (PdNPs)/plated Pd (Pd plate)/multiwalled carbon nanotubes (MWCNTs)/Au electrode was prepared for fabricating an amperometric biosensor and a biofuel cell (BFC) of uric acid.

Technology Process of Furan-3-boronic acid

There total 5 articles about Furan-3-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3-bromofurane (22037-28-1) → furan-3-boronic acid (55552-70-0)

Guidance literature:

3-bromofurane; With n-butyllithium; Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - -2 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; hexane; for 0.75h;

DOI:10.1016/j.bmcl.2006.07.074

Reference yield: 67.0%

3-bromofurane (22037-28-1) + Triisopropyl borate (5419-55-6) → furan-3-boronic acid (55552-70-0)

Guidance literature:

3-bromofurane; With n-butyllithium;

Triisopropyl borate;

With hydrogenchloride; In water;

DOI:10.3987/COM-09-S(S)17

Reference yield:

C6H9BO3 → furan-3-boronic acid (55552-70-0)

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran; hexane; at 20 ℃; pH=3 - 5;

DOI:10.1002/chem.201302451

upstream raw materials:

3-bromofurane

Triisopropyl borate

tetrahydroxydiboron

Downstream raw materials:

N-<2-(3-furyl)benzyl>benzamide

7-Chloro4-(furan-3-yl)quinoline

4-furan-3-yl-3-methoxycarbonylmethyl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester

4-(phenylamino)butyronitrile