Technology Process of 2-{12-[3-hydroxy-5-(2-methyloctan-2-yl)phenoxy]dodecyloxy}propane-1,3-diol
There total 4 articles about 2-{12-[3-hydroxy-5-(2-methyloctan-2-yl)phenoxy]dodecyloxy}propane-1,3-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethanol; water;
at 80 - 90 ℃;
for 3h;
DOI:10.1021/jm200529h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: Reflux; Inert atmosphere
2.1: potassium fluoride; potassium carbonate / acetone / 0.5 h / Reflux; Inert atmosphere
2.2: 48 h / Reflux; Inert atmosphere
3.1: hydrogenchloride / ethanol; water / 3 h / 80 - 90 °C
With
hydrogenchloride; potassium fluoride; sodium hydride; potassium carbonate;
In
tetrahydrofuran; ethanol; water; acetone;
DOI:10.1021/jm200529h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: boron tribromide / dichloromethane
2.1: potassium fluoride; potassium carbonate / acetone / 0.5 h / Reflux; Inert atmosphere
2.2: 48 h / Reflux; Inert atmosphere
3.1: hydrogenchloride / ethanol; water / 3 h / 80 - 90 °C
With
hydrogenchloride; potassium fluoride; boron tribromide; potassium carbonate;
In
ethanol; dichloromethane; water; acetone;
DOI:10.1021/jm200529h
