Technology Process of C17H24N2O3*ClH
There total 7 articles about C17H24N2O3*ClH which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
1,4-dioxane;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: diisobutylaluminium hydride / hexanes / -78 - 0 °C
1.2: 0 - 20 °C
2.1: 2,4,6-trimethyl-pyridine; benzoic acid; (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine / ethanol / 2 h
3.1: hydrogen / Raney nickel / methanol / 2068.65 Torr
4.1: N-ethyl-N,N-diisopropylamine / dichloromethane
5.1: Jones reagent
6.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 24 h / 20 °C
7.1: hydrogenchloride / 1,4-dioxane
With
hydrogenchloride; Jones reagent; hydrogen; diisobutylaluminium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
(2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; 2,4,6-trimethyl-pyridine; benzoic acid;
In
1,4-dioxane; methanol; hexanes; ethanol; dichloromethane;
2.1: Michael Condensation;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 2,4,6-trimethyl-pyridine; benzoic acid; (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine / ethanol / 2 h
2: hydrogen / Raney nickel / methanol / 2068.65 Torr
3: N-ethyl-N,N-diisopropylamine / dichloromethane
4: Jones reagent
5: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 24 h / 20 °C
6: hydrogenchloride / 1,4-dioxane
With
hydrogenchloride; Jones reagent; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
(2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; 2,4,6-trimethyl-pyridine; benzoic acid;
In
1,4-dioxane; methanol; ethanol; dichloromethane;
1: Michael Condensation;