(+)-(S)-3-oxo-1-cylcohexanecarboxylic acid

Base Information

• Chemical Name: (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid
• CAS No.: 21531-46-4
• Molecular Formula: C₇H₁₀O₃
• Molecular Weight: 142.155
• Mol file: 21531-46-4.mol

Synonyms:(+)-(S)-3-oxo-1-cylcohexanecarboxylic acid

Chemical Property of (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(1S)-3-oxocyclohexane-1-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid

There total 21 articles about (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-(5-methyl-2-furanyl)cyclohexanone → (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid (21531-46-4)

Guidance literature:

With ozone; In methanol; at -78 ℃; for 0.5h;

DOI:10.1002/asia.201000589

Reference yield: 87.0%

(S)-ethyl 3-oxocyclohexanecarboxylate → (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid (21531-46-4)

Guidance literature:

With lithium hydroxide; In methanol; water; at 20 ℃; for 6h;

DOI:10.1039/c7gc02215h

Reference yield:

cyclohexen-3-one-1-carboxylic acid (24079-79-6) → (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid (21531-46-4)

Guidance literature:

With NADPH; alpha-D-glucopyranose; sodium hydroxide; In aq. phosphate buffer; at 32.5 ℃; for 22h; pH=8; Enzymatic reaction;

upstream raw materials:

(1S,3S)-3-hydroxycyclohexane-1-carboxylic acid

(S)-methyl 3-oxocyclohexanecarboxylates

isopropyl 3-oxocyclohex-1-ene-1-carboxylate

(1S,3S)-3-hydroxycyclohexane-1-carboxylic acid isopropyl ester

Downstream raw materials:

(1S,3S)-cis-1-amino-1,3-cyclohexanedicarboxylic acid

(1S,3R)-1-Amino-cyclohexane-1,3-dicarboxylic acid

methyl (S)-3,3-dimethoxycyclohexanecarboxylate