Technology Process of tert-butyldiphenylsilyl 2-azido-2,6-dideoxy-β-D-glucopyranoside
There total 3 articles about tert-butyldiphenylsilyl 2-azido-2,6-dideoxy-β-D-glucopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: pyridine / 20 °C
2: piperidine / tetrahydrofuran / 2.5 h
3: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 60 °C
4: sodium methylate / methanol; dichloromethane
5: pyridine / 2 h / 0 °C
6: sodium iodide / butanone / 6 h / Reflux
7: sodium cyanoborohydride / diethylene glycol dimethyl ether / 7 h / Reflux
With
piperidine; 1H-imidazole; sodium methylate; sodium cyanoborohydride; sodium iodide;
In
tetrahydrofuran; pyridine; methanol; dichloromethane; diethylene glycol dimethyl ether; N,N-dimethyl-formamide; butanone;
DOI:10.1016/j.carres.2012.02.015
- Guidance literature:
-
Multi-step reaction with 8 steps
1: imidazole-1-sulfonyl azide hydrochloride; copper(II) sulfate; triethylamine / methanol / 1.5 h
2: pyridine / 20 °C
3: piperidine / tetrahydrofuran / 2.5 h
4: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 60 °C
5: sodium methylate / methanol; dichloromethane
6: pyridine / 2 h / 0 °C
7: sodium iodide / butanone / 6 h / Reflux
8: sodium cyanoborohydride / diethylene glycol dimethyl ether / 7 h / Reflux
With
piperidine; 1H-imidazole; imidazole-1-sulfonyl azide hydrochloride; sodium methylate; sodium cyanoborohydride; copper(II) sulfate; triethylamine; sodium iodide;
In
tetrahydrofuran; pyridine; methanol; dichloromethane; diethylene glycol dimethyl ether; N,N-dimethyl-formamide; butanone;
DOI:10.1016/j.carres.2012.02.015
