3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole

Base Information

• Chemical Name: 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole
• CAS No.: 110607-56-2
• Molecular Formula: C₁₃H₁₃Cl₂N₃O₃
• Molecular Weight: 330.171
• Mol file: 110607-56-2.mol

Synonyms:3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole

Chemical Property of 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole

There total 2 articles about 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-hydroxy-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole (110626-11-4) + Ethyl 2-bromopropionate (535-11-5,41978-69-2) → 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole (110607-56-2)

Guidance literature:

With sodium methylate; In methanol; dimethyl sulfoxide; for 4h; at steam bath temperature;

Reference yield:

1-(2,4-dichloro-phenyl)-semicarbazide (14657-26-2) → 3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole (110607-56-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / p-toluenesulfonic acid / 16 h / steam bath temperature

2: 87 percent / sodium methoxide / dimethylsulfoxide; methanol / 4 h / at steam bath temperature

With sodium methylate; toluene-4-sulfonic acid; In methanol; dimethyl sulfoxide;

Reference yield:

3-(1-ethoxycarbonylethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole (110607-56-2) → 3-(1-carboxyethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole (110607-75-5)

Guidance literature:

With potassium hydroxide; In ethanol;

upstream raw materials:

3-hydroxy-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole

Ethyl 2-bromopropionate

1-(2,4-dichloro-phenyl)-semicarbazide

Downstream raw materials:

3-(1-carboxyethoxy)-1-(2,4-dichlorophenyl)-1,2,4-1H-triazole