2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene

Base Information

• Chemical Name: 2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene
• CAS No.: 749862-88-2
• Molecular Formula: C₂₁H₃₄OSi
• Molecular Weight: 330.586
• Mol file: 749862-88-2.mol

Synonyms:2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene

Chemical Property of 2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene

There total 1 articles about 2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

1-Phenylprop-1-yne (673-32-5) + butyraldehyde (123-72-8) + 7,7-di-tert-butyl-7-silabicyclo[4.1.0]heptane (130451-35-3) → 2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene (749862-88-2) + 2,2-di-tert-butyl-4-methyl-3-phenyl-5-propyl-2,5-dihydro-[1,2]oxasilole

Guidance literature:

1-Phenylprop-1-yne; 7,7-di-tert-butyl-7-silabicyclo[4.1.0]heptane; With silver orthophosphate; In toluene; for 1.5h;

butyraldehyde; With copper(II) bis(trifluoromethanesulfonate); In toluene; for 13h;

DOI:10.1021/ja047498f

Reference yield: 84.0%

2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene (749862-88-2) → (3RS,4RS,5RS)-2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentane

Guidance literature:

With palladium dihydroxide; hydrogen; In ethanol; for 120h;

DOI:10.1021/ja047498f

Reference yield:

2,2-di-tert-butyl-3-methyl-4-phenyl-5-propyloxasilacyclopentene (749862-88-2) → (1RS,2SR,3RS)-3-phenyl-2,4-heptanediol

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / H₂; Pd(OH)2/C / ethanol / 120 h

2: 89 percent / KH; 1-methyl-2-pyrrolidinone; tert-butylhydroperoxide / TBAF / tetrahydrofuran; toluene / 7 h / 75 °C

With 1-methyl-pyrrolidin-2-one; tert.-butylhydroperoxide; palladium dihydroxide; hydrogen; potassium hydride; tetrabutyl ammonium fluoride; In tetrahydrofuran; ethanol; toluene;

DOI:10.1021/ja047498f

upstream raw materials:

1-Phenylprop-1-yne

butyraldehyde

7,7-di-tert-butyl-7-silabicyclo[4.1.0]heptane