1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct

Base Information

• Chemical Name: 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct
• CAS No.: 1455481-88-5
• Molecular Formula: C₂₀H₃₁F₄N₂P
• Molecular Weight: 406.447
• Mol file: 1455481-88-5.mol

Synonyms:1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct

Chemical Property of 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct

There total 4 articles about 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

dichloro[4-(4-propylcyclohexyl)phenyl]phosphine (1455481-70-5) + 2,2-difluoro-1,3-dimethyl-imidazolidine (220405-40-3) → 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct (1455481-88-5)

Guidance literature:

In tetrahydrofuran; at -40 - 20 ℃; for 18h; Inert atmosphere;

DOI:10.1016/j.tet.2013.07.062

Reference yield:

4-(4-propylcyclohexyl)-1-bromobenzene (86579-53-5,167858-55-1) → 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct (1455481-88-5)

Guidance literature:

Multi-step reaction with 4 steps

1: magnesium / tetrahydrofuran / 1 h / Inert atmosphere; Reflux

2: tetrahydrofuran / 16 h / -20 - 20 °C / Inert atmosphere

3: hydrogenchloride / diethyl ether / 20 °C / Inert atmosphere

4: tetrahydrofuran / 18 h / -40 - 20 °C / Inert atmosphere

With hydrogenchloride; magnesium; In tetrahydrofuran; diethyl ether;

DOI:10.1016/j.tet.2013.07.062

Reference yield:

C15H21BrMg (1455481-71-6) → 1,3-dimethylimidazolin-2-ylidene-tetrafluoro[4-(4-propylcyclohexyl)phenyl]phosphorane adduct (1455481-88-5)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / 16 h / -20 - 20 °C / Inert atmosphere

2: hydrogenchloride / diethyl ether / 20 °C / Inert atmosphere

3: tetrahydrofuran / 18 h / -40 - 20 °C / Inert atmosphere

With hydrogenchloride; In tetrahydrofuran; diethyl ether;

DOI:10.1016/j.tet.2013.07.062

upstream raw materials:

4-(4-propylcyclohexyl)-1-bromobenzene

dichloro[4-(4-propylcyclohexyl)phenyl]phosphine

2,2-difluoro-1,3-dimethyl-imidazolidine

C₁₅H₂₁BrMg