N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine

Base Information

• Chemical Name: N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine
• CAS No.: 937020-96-7
• Molecular Formula: C₁₅H₂₁FN₂O₂
• Molecular Weight: 280.342
• Mol file: 937020-96-7.mol

Synonyms:N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine

Chemical Property of N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine

There total 3 articles about N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]hydrazine (843651-80-9) → N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine (937020-96-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jm050538l

Reference yield:

2-(4-fluorophenyl)-1-propene (350-40-3) → N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine (937020-96-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NBS / CCl₄ / Heating

2: 24 percent / NEt₃ / methanol / 3 h / Heating

3: 98 percent / N,N-diisopropylethylamine / dimethylformamide / 20 °C

With N-Bromosuccinimide; triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm050538l

Reference yield:

1-(3-bromoprop-1-en-2-yl)-4-fluorobenzene (132927-05-0) → N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]-N'-methylhydrazine (937020-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 24 percent / NEt₃ / methanol / 3 h / Heating

2: 98 percent / N,N-diisopropylethylamine / dimethylformamide / 20 °C

With triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm050538l

upstream raw materials:

N-tert-butoxycarbonyl-N'-[2-(4-fluorophenyl)allyl]hydrazine

2-(4-fluorophenyl)-1-propene

1-(3-bromoprop-1-en-2-yl)-4-fluorobenzene