Technology Process of C25H27N3O
There total 16 articles about C25H27N3O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 82 percent / NaH
2: LiNEt2 / tetrahydrofuran / -78 °C
3: 75 percent / LiBH4
With
lithium borohydride; lithium diethylamide; sodium hydride;
In
tetrahydrofuran;
1: Wittig reaction / 2: Michael reaction;
DOI:10.1039/b310274b
- Guidance literature:
-
Multi-step reaction with 12 steps
1: 78 percent / pyridine
2: 88 percent / Na; NH3 / tetrahydrofuran / 0.5 h
3: 3 Angstroem molecular sieves / 24 h
4: 80 percent / TFA / CH2Cl2 / 6 h / -78 - 20 °C
5: 75 percent / 70 °C
6: 87 percent / NaH / 0 °C
7: 96 percent / TBAF
8: 82 percent / NaH
9: LiNEt2 / tetrahydrofuran / -78 °C
10: 75 percent / LiBH4
With
pyridine; lithium borohydride; 3 A molecular sieve; lithium diethylamide; tetrabutyl ammonium fluoride; ammonia; sodium; sodium hydride; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane;
5: Pictet-Spengler reaction / 9: Swern oxidation / 10: Wittig reaction / 11: Michael reaction;
DOI:10.1039/b310274b