(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Base Information

Chemical Name:(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester
CAS No.:1257409-41-8
Molecular Formula:C₆₃H₈₃NO₁₅S
Molecular Weight:1126.42
Hs Code.:

(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Synonyms:(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Suppliers and Price of (3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

There total 6 articles about (3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.3%

: 1257409-37-2
(3β,18β,20β)-3-{2-[methyl (2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyl)uronate]ethylamino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

: 1490-25-1
succinic acid monomethylester chloride

: 1257409-41-8
(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 1.58333h;

Reference yield:

: 1257409-36-1
methyl (1-O-(2-iodoethyl)-2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyl)uronate

: 1257409-41-8
(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 45 - 50 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.58 h / 0 - 20 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.3762/bjoc.8.79

Reference yield:

: 68354-87-0
1-Thio-1-desoxy-(2,3,4-tri-O-acetyl-β-D-glucuronsaeuremethylester)

: 1257409-41-8
(3S,18R,20S)-3-{N-(4-methoxy-1,4-dioxobutyl)-N-[2-S-(methyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosyluronate)ethyl]amino}-11-oxo-olean-12-en-29-oic acid diphenylmethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydride / hexane; N,N-dimethyl-formamide / -5 °C / Inert atmosphere

2: sodium iodide / acetone / 16 h / 4 °C / Inert atmosphere; Darkness

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 45 - 50 °C / Inert atmosphere

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.58 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; N-ethyl-N,N-diisopropylamine; sodium iodide; In hexane; dichloromethane; N,N-dimethyl-formamide; acetone; 2: Finkelstein reaction;
DOI:10.3762/bjoc.8.79