6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane

Base Information

• Chemical Name: 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane
• CAS No.: 1443343-67-6
• Molecular Formula: C₂₄H₂₆OSi
• Molecular Weight: 358.555
• Mol file: 1443343-67-6.mol

Synonyms:6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane

Chemical Property of 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane

There total 6 articles about 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[1-(2,6-dimethylphenyl)but-3-enyloxy]diphenylsilane (1443335-80-5) → trans-5-(2,6-dimethylphenyl)-3-methyl-2,2-diphenyl-1,2-oxasilolane + 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane (1443343-67-6)

Guidance literature:

With norbornene; [Rh(nbd)Cl]₂; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; at -78 - 0 ℃; for 26h; diastereoselective reaction;

DOI:10.1021/ol401464n

Reference yield:

[1-(2,6-dimethylphenyl)but-3-enyloxy]diphenylsilane (1443335-80-5) → 5-(2,6-dimethylphenyl)-3-methyl-2,2-diphenyl-1,2-oxasilolane + 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane (1443343-67-6)

Guidance literature:

With 2,2-diphenyl-1-picrylhydrazyl; norbornene; [Rh(nbd)Cl]₂; In tetrahydrofuran; at 20 ℃; for 24h; regioselective reaction;

DOI:10.1021/ol401464n

Reference yield:

diphenylsilane (775-12-2) → 5-(2,6-dimethylphenyl)-3-methyl-2,2-diphenyl-1,2-oxasilolane + 6-(2,6-dimethylphenyl)-2,2-diphenyl-1,2-oxasilinane (1443343-67-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dichloromethane / 0.08 h / 0 °C

1.2: 1 h / 0 - 20 °C

2.1: dichloromethane / 0.08 h / 0 °C

2.2: 1 h / 0 - 20 °C

3.1: 2,2-diphenyl-1-picrylhydrazyl; [Rh(nbd)Cl]₂; norbornene / tetrahydrofuran / 24 h / 20 °C

With 2,2-diphenyl-1-picrylhydrazyl; norbornene; [Rh(nbd)Cl]₂; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol401464n

upstream raw materials:

[1-(2,6-dimethylphenyl)but-3-enyloxy]diphenylsilane

diphenylsilane

bromo-diphenyl-silane

Downstream raw materials:

1-(2,6-dimethylphenyl)butane-1,4-diol