1-methylindol-3-yl 2-aminophenyl sulphide

Base Information

• Chemical Name: 1-methylindol-3-yl 2-aminophenyl sulphide
• CAS No.: 120105-54-6
• Molecular Formula: C₁₅H₁₄N₂S
• Molecular Weight: 254.356
• Mol file: 120105-54-6.mol

Synonyms:1-methylindol-3-yl 2-aminophenyl sulphide

Chemical Property of 1-methylindol-3-yl 2-aminophenyl sulphide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-methylindol-3-yl 2-aminophenyl sulphide

There total 7 articles about 1-methylindol-3-yl 2-aminophenyl sulphide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-methylindol-3-yl 2-nitrophenyl sulphide (58421-65-1) → 1-methylindol-3-yl 2-aminophenyl sulphide (120105-54-6)

Guidance literature:

With hydrazine hydrate; palladium on activated charcoal; In ethanol; for 3h; Heating;

Reference yield: 78.0%

1-methylindole (603-76-9) + 2-Aminophenyl disulfide (1141-88-4) → 1-methylindol-3-yl 2-aminophenyl sulphide (120105-54-6)

Guidance literature:

2-Aminophenyl disulfide; With ammonium peroxydisulfate; In methanol; at 70 ℃; for 3h;

1-methylindole; In methanol; at 20 - 70 ℃;

DOI:10.1039/c3ob41601a

Reference yield: 23.0%

1-methylindol-3-yl 2-nitrophenyl sulphide (58421-65-1) + triethyl phosphite (122-52-1) → 1-methyl-3′H-spiro[indole-3,2′-[1,3]benzothiazole]-2(1H)-one (58421-72-0) + 6-methylindolo<2,3-b><1,4>benzothazine + 1-methylindol-3-yl 2-aminophenyl sulphide (120105-54-6) + 1-methylindol-3-yl o-ethylaminophenyl sulphide

Guidance literature:

for 4h; Product distribution; Mechanism; Heating; also in cumene; other (o-nitroarylthio)indoles, other products;

upstream raw materials:

1-methylindol-3-yl 2-nitrophenyl sulphide

triethyl phosphite

bis(2-nitrophenyl)disulfide

2-nitrobenzenesulfenyl chloride