allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside

Base Information

• Chemical Name: allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside
• CAS No.: 197916-11-3
• Molecular Formula: C₄₆H₆₀O₁₁
• Molecular Weight: 788.976
• Mol file: 197916-11-3.mol

Synonyms:allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside

Chemical Property of allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside

There total 1 articles about allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(S)-2-Methylbutyric acid (1730-91-2) + allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-α-L-rhamnopyranoside (197916-10-2) → allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside (197916-11-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1021/jo971413u

Reference yield:

allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside (197916-11-3) → (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranose (197916-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (Ph₃P)3RhCl / H₂O; ethanol / Heating

2: 994 mg / HgCl₂; HgO / H₂O; acetone / 2 h

With mercury dichloride; mercury(II) oxide; Wilkinson's catalyst; In ethanol; water; acetone; 1: Isomerization / 2: Hydrolysis;

DOI:10.1021/jo971413u

Reference yield:

allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranoside (197916-11-3) → (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranose 1-trichloroacetimidate (197916-13-5)

Guidance literature:

Multi-step reaction with 3 steps

1: (Ph₃P)3RhCl / H₂O; ethanol / Heating

2: 994 mg / HgCl₂; HgO / H₂O; acetone / 2 h

3: Cs₂CO₃ / CH₂Cl₂ / 9 h

With caesium carbonate; mercury dichloride; mercury(II) oxide; Wilkinson's catalyst; In ethanol; dichloromethane; water; acetone; 1: Isomerization / 2: Hydrolysis / 3: Addition;

DOI:10.1021/jo971413u

upstream raw materials:

(S)-2-Methylbutyric acid

allyl (2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-α-L-rhamnopyranoside

Downstream raw materials:

(2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranose

(2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl)-(1->3)-2,4-di-O-[(2S)-2-methylbutyryl]-α-L-rhamnopyranose 1-trichloroacetimidate