(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

Base Information

Chemical Name:(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid
CAS No.:1416772-46-7
Molecular Formula:C₂₅H₂₈N₂O₃
Molecular Weight:404.509
Hs Code.:

Synonyms:(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

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Technology Process of (2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

There total 15 articles about (2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: C₅₀H₅₅N₃O₅S

: 1416772-46-7
(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

Reference yield: 96.0%

: 1416772-51-4
(1R,2S)-2-((N-benzyl-2,4,6-trimethylphenyl)sulfonamido)-1-phenylpropyl(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoate

: 1416772-46-7
(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

Guidance literature:: (1R,2S)-2-((N-benzyl-2,4,6-trimethylphenyl)sulfonamido)-1-phenylpropyl(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoate; With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 20 ℃; for 24h; Inert atmosphere; Schlenk technique;

With hydrogenchloride;
DOI:10.1021/ml300385q

Reference yield:

: 1416772-63-8
C₂₅H₂₈N₂O₂

: 1416772-46-7
(2R,3S,4S)-4-(dibenzylamino)-3-hydroxy-2-methyl-5-(pyridin-3-yl)pentanoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2,3-Dimethyl-2-butene; In water; tert-butyl alcohol; at 20 ℃; for 0.75h; Inert atmosphere; Schlenk technique;
DOI:10.1021/ml300385q