(s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid

Base Information

Chemical Name:(s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid
CAS No.:204688-61-9
Molecular Formula:C11H19NO4
Molecular Weight:229.276
Hs Code.:2933990090
European Community (EC) Number:675-897-0
DSSTox Substance ID:DTXSID30363615
Wikidata:Q72450635
Mol file:204688-61-9.mol

Synonyms:204688-61-9;(s)-2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(S)-(1-Boc-Pyrrolidin-3-yl)-acetic acid;s-1-boc-pyrrolidin-3-acetic acid;(S)-N-Boc-3-pyrrolidineacetic acid;(s)-3-carboxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;2-[(3S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid;3-PYRROLIDINEACETIC ACID, 1-[(1,1-DIMETHYLETHOXY)CARBONYL]-, (3S)-;2-[(3S)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]acetic acid;(S)-1-N-Boc-3-pyrrolidineacetic acid;(S)-(1-Boc-pyrrolidin-3-yl)acetic acid;(S)-1-Boc-3-Carboxymethylpyrrolidine;MFCD05861546;(3S)-1-BOC-3-PYRROLIDINEACETIC ACID;SCHEMBL874037;DTXSID30363615;AMY14492;CS-B0997;(s)-n-boc-pyrrolidine-3-acetic acid;AKOS015898194;AC-6303;GS-3891;(S)-2-(1-BOC-pyrrolidin-3-yl)acetic acid;EN300-155897;(s)-1-tert-butoxycarbonylpyrrolidine-3-acetic acid;(S)-(1-Boc-pyrrolidin-3-yl)-acetic acid, AldrichCPR;(s)-2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)aceticacid;[(3s)-1-(tert-butoxycarbonyl)pyrrolidin-3-yl]acetic acid;(S)-2-(1-(tert-Butoxycarbonyl)-pyrrolidin-3-yl)acetic acid;(S)-3-carboxymethyl-pyrrolidine-1-carboxylic acid tert butyl ester;((3S)-1-{[(1,1-dimethylethyl)oxy]carbonyl}-3-pyrrolidinyl)acetic acid

Suppliers and Price of (s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(S)-2-(1-(tert-Butoxycarbonyl)-pyrrolidin-3-yl)acetic acid 95+%
5g
$ 755.00

Matrix Scientific
(S)-2-(1-(tert-Butoxycarbonyl)-pyrrolidin-3-yl)acetic acid 95+%
1g
$ 216.00

Crysdot
(S)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)aceticacid 97%
10g
$ 347.00

Crysdot
(S)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)aceticacid 97%
100g
$ 1931.00

Crysdot
(S)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)aceticacid 97%
25g
$ 644.00

Chemenu
2-[(3S)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]aceticacid 97%
25g
$ 715.00

Chemenu
2-[(3S)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]aceticacid 97%
5g
$ 237.00

Chemenu
2-[(3S)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]aceticacid 97%
10g
$ 385.00

Biosynth Carbosynth
(S)-(1-boc-pyrrolidin-3-yl)-acetic acid
250 g
$ 100.00

Biosynth Carbosynth
(S)-(1-boc-pyrrolidin-3-yl)-acetic acid
500 g
$ 160.00

Total 61 raw suppliers

Chemical Property of (s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid

Chemical Property:

Vapor Pressure:4.5E-06mmHg at 25°C
Refractive Index:1.491
Boiling Point:357.392 °C at 760 mmHg
PKA:4.65±0.10(Predicted)
Flash Point:169.945 °C
PSA：66.84000
Density:1.151 g/cm³
LogP:1.65600
Storage Temp.:2-8°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:229.13140809
Heavy Atom Count:16
Complexity:282

Purity/Quality:

99% ^*data from raw suppliers

(S)-2-(1-(tert-Butoxycarbonyl)-pyrrolidin-3-yl)acetic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)CC(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N1CC[C@H](C1)CC(=O)O

Technology Process of (s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid

There total 4 articles about (s)-2-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2-[(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]propanedioic acid

: 204688-61-9
2‐[(3S)‐1‐[(tert‐butoxy)carbonyl]pyrrolidin‐3‐yl]acetic acid

Guidance literature:: In dimethyl sulfoxide; toluene; for 16h; Reflux;

Reference yield:

: 2-[(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]propanedioic acid ethyl ester

: 204688-61-9
2‐[(3S)‐1‐[(tert‐butoxy)carbonyl]pyrrolidin‐3‐yl]acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / water; tetrahydrofuran / 24 h / 45 °C

2: toluene; dimethyl sulfoxide / 16 h / Reflux

With potassium hydroxide; In tetrahydrofuran; water; dimethyl sulfoxide; toluene;

Reference yield:

: 101469-92-5,83220-73-9
(S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester

: 204688-61-9
2‐[(3S)‐1‐[(tert‐butoxy)carbonyl]pyrrolidin‐3‐yl]acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / toluene / 1.33 h / -10 - 20 °C

2.1: sodium / ethanol / 0.5 h / 20 °C

2.2: 16 h / Reflux

3.1: potassium hydroxide / water; tetrahydrofuran / 24 h / 45 °C

4.1: toluene; dimethyl sulfoxide / 16 h / Reflux

With sodium; triethylamine; potassium hydroxide; In tetrahydrofuran; ethanol; water; dimethyl sulfoxide; toluene;