Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate

Base Information

Chemical Name:Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate
CAS No.:143979-15-1
Molecular Formula:C10H17NO4^.C12H23N
Molecular Weight:396.56
Hs Code.:29242990
DSSTox Substance ID:DTXSID10373176
Mol file:143979-15-1.mol

Synonyms:143979-15-1;Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate;Boc-L-Allylglycine.DCHA;Boc-Allyl-L-glycine dicyclohexylammonium salt;Boc-allyl-Gly-OH (dicyclohexylammonium) salt;N-cyclohexylcyclohexanamine;(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pent-4-enoic acid;C22H40N2O4;BOC-L-ALLYLGLYCINE DCHA;Boc-L-Allylglycine dicyclohexylaminoium salt;Boc-L-allylglycine . DCHA;MFCD01321013;Boc-Algly-OH.DCHA;DTXSID10373176;VMCGMPITVQIMGK-ZLTKDMPESA-N;AKOS015948714;AC-7944;CS-W009390;HY-W008674;AS-11357;D82221;A808148;Dicyclohexylamine (S)-2-(BOC-amino)pent-4-enoate;J-007890;Boc-L-Allylglycine DCHA (Boc-L-Gly(All)-OH.DCHA);Boc-allyl-Gly-OH (dicyclohexylammonium) salt, >=98.0% (TLC);dicyclohexylamine (S)-2-(tert-butoxycarbonylamino)pent-4-enoate;Dicyclohexylamine(S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate;(2S)-2-[(tert-Butoxycarbonyl)amino]pent-4-enoic acid--N-cyclohexylcyclohexanamine (1/1);(S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid dicyclohexylammonium salt;(2S)-2-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-4-pentenoic acid - N-cyclohexylcyclohexanamine (1:1)

Suppliers and Price of Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Boc-allyl-L-glycine dicyclohexylammonium salt 99+%
1g
$ 222.00

Usbiological
Boc-L-Allylglycine
250mg
$ 368.00

TRC
Dicyclohexylamine(S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoate
100mg
$ 75.00

Sigma-Aldrich
Boc-allyl-Gly-OH (dicyclohexylammonium) salt ≥98.0% (TLC)
250mg
$ 126.00

Matrix Scientific
Boc-L-allylglycine . DCHA
25g
$ 398.00

Matrix Scientific
Boc-L-allylglycine . DCHA
1g
$ 39.00

Matrix Scientific
Boc-L-allylglycine . DCHA
5g
$ 119.00

Iris Biotech GmbH
Boc-L-AllylGly-OH*DCHA
1 g
$ 101.25

Iris Biotech GmbH
Boc-L-AllylGly-OH*DCHA
25 g
$ 1080.00

Iris Biotech GmbH
Boc-L-AllylGly-OH*DCHA
5 g
$ 270.00

Total 58 raw suppliers

Chemical Property of Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate

Chemical Property:

Vapor Pressure:7.54E-05mmHg at 25°C
Refractive Index:1.479
Boiling Point:352 °C at 760 mmHg
Flash Point:166.7 °C
PSA：87.66000
Density:1.108g/cm³
LogP:5.56360
Storage Temp.:Store at 0°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:396.29880776
Heavy Atom Count:28
Complexity:371

Purity/Quality:

97% ^*data from raw suppliers

Boc-allyl-L-glycine dicyclohexylammonium salt 99+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC=C)C(=O)O.C1CCC(CC1)NC2CCCCC2
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC=C)C(=O)O.C1CCC(CC1)NC2CCCCC2
Uses 2-Allyl-N-Boc-L-glycine dicyclohexylamine salt is used as pharmaceutical intermediate.

Technology Process of Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate

There total 1 articles about Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1069-48-3,7685-44-1
rac-allylglycine

: 24424-99-5
di-tert-butyl dicarbonate

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 143979-15-1
2-tert-Butoxycarbonylamino-pent-4-enoic acid; compound with dicyclohexyl-amine

Guidance literature:: With sodium hydroxide; In diethyl ether; water; for 2h;
DOI:10.1016/S0040-4020(01)80055-7

Reference yield: 84.0%

: 143979-15-1
L-(alpha-allyl)glycine dicyclohexylamine

: H-Ala-Leu-OBn hydrochloride

: benzyl ((S)-2-((tert-butoxycarbonyl)amino)pent-4-enoyl)-L-alanyl-L-leucinate

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c02904

Reference yield:

: 143979-15-1
2-tert-Butoxycarbonylamino-pent-4-enoic acid; compound with dicyclohexyl-amine

: 123457-13-6,123536-96-9,125075-19-6
p-nitrobenzyl (2S*,5R*,7S*)-7-<<(1,1-dimethylethoxy)carbonyl>amino>-8-oxo-4-thia-1-azabicyclo<3.3.0>octane-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide / 72 h / Ambient temperature

2: 68.8 g / NaOAc / acetic acid / 24 h / Ambient temperature

3: NaHCO₃ / dimethylformamide / 48 h / Ambient temperature

With sodium acetate; sodium hydrogencarbonate; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80055-7