BOC-D-Arg(Tos)-OH

Base Information

• Chemical Name: BOC-D-Arg(Tos)-OH
• CAS No.: 61315-61-5
• Molecular Formula: C18H28N4O6S
• Molecular Weight: 428.51
• Hs Code.: 29350090
• Mol file: 61315-61-5.mol

Synonyms:N(alpha)-BOC-N(omega)-tosyl-D-arginine; BOC-N-omega-4-toluenesulfonyl-D-arginine

Chemical Property of BOC-D-Arg(Tos)-OH

Chemical Property:

• Melting Point: 90-100 ºC
• PKA: 3.95±0.21(Predicted)
• PSA: 166.06000
• Density: 1.31g/cm3
• LogP: 3.90900
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

Boc-D-Arg(Tos)-OH Novabiochem? ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Boc-D-Arg(Tos)-OH, is an Arginine derivative, used in various chemical synthesis, and peptide chemistry.

Technology Process of BOC-D-Arg(Tos)-OH

There total 1 articles about BOC-D-Arg(Tos)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Nα-tert-butyloxycarbonyl-Nω-toluenesulfonyl-D-arginine (61315-61-5)

Guidance literature:

Reference yield: 95.0%

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride (7524-50-7) + Nα-tert-butyloxycarbonyl-Nω-toluenesulfonyl-D-arginine (61315-61-5) → Boc-D-Arg(Tos)-Phe-OMe (100304-71-0)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In triethylamine; N,N-dimethyl-formamide; at 5 ℃;

DOI:10.1248/cpb.33.4865

Reference yield: 85.9%

Nα-tert-butyloxycarbonyl-Nω-toluenesulfonyl-D-arginine (61315-61-5) + N1-benzyloxycarbonyl-1,8-octanediamine hydrochloride → N1-benzyloxycarbonyl-N8-(Nα-t-butoxycarbonyl-Ng-tosyl-D-arginyl)-1,8-octanediamine (205874-91-5)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1246/bcsj.71.699

Downstream raw materials:

Boc-D-Arg(Tos)-Phe-OMe

Boc-D-Arg(Tos)-Phe-N(CH₂CH=CH₂)2

Boc-D-Arg(Tos)-Phe-NHCH₂CH=CH₂

Boc-D-Arg(Tos)-NH₂

Refernces