3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

Base Information

Chemical Name:3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide
CAS No.:310896-84-5
Molecular Formula:C₂₀H₂₉NOSi₂
Molecular Weight:355.627
Hs Code.:

Synonyms:3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

Suppliers and Price of 3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

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Chemical Property of 3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

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Technology Process of 3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

There total 1 articles about 3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66224-70-2
3-(trimethylsilyl)propynoyl chloride

: 192655-92-8
((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amine

: 310896-84-5
3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

Guidance literature:: DOI:10.1021/ol0065221

Reference yield: 79.0%

: 310896-84-5
3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

: 310896-90-3
1-((R)-1-Phenyl-ethyl)-3,4-bis-[1-trimethylsilanyl-meth-(Z)-ylidene]-pyrrolidin-2-one

Guidance literature:: With titanium(IV) isopropylate; isopropylmagnesium chloride; In diethyl ether; at -20 ℃; for 4h;
DOI:10.1021/ol0065221

Reference yield:

: 310896-84-5
3-Trimethylsilanyl-propynoic acid ((R)-1-phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amide

: (3aS,4R,8S,8aR)-2-Phenyl-6-((R)-1-phenyl-ethyl)-4,8-bis-trimethylsilanyl-3a,4,6,7,8,8a-hexahydro-pyrrolo[3,4-f]isoindole-1,3,5-trione

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / Ti(O-i-Pr)4; i-PrMgCl / diethyl ether / 4 h / -20 °C

2: 22 percent / toluene / Heating

With titanium(IV) isopropylate; isopropylmagnesium chloride; In diethyl ether; toluene; 1: Cyclization / 2: Diels-Alder reaction;
DOI:10.1021/ol0065221