Technology Process of 2,3-bis(thiophen-2-yl)-N-cyclohexylmaleimide
There total 5 articles about 2,3-bis(thiophen-2-yl)-N-cyclohexylmaleimide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
ethanol; water; toluene;
at 90 ℃;
Inert atmosphere;
DOI:10.1002/pola.24792
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1,1,1,3,3,3-hexamethyl-disilazane; benzene
2: bromine; acetic acid
3: bromine; sodium acetate; acetic acid
4: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; water; toluene / 90 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); bromine; sodium acetate; potassium carbonate; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane; benzene;
In
ethanol; water; toluene;
4: Suzuki-Miyaura cross-coupling;
DOI:10.1002/pola.24792
- Guidance literature:
-
Multi-step reaction with 5 steps
1: ethyl acetate
2: 1,1,1,3,3,3-hexamethyl-disilazane; benzene
3: bromine; acetic acid
4: bromine; sodium acetate; acetic acid
5: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; water; toluene / 90 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); bromine; sodium acetate; potassium carbonate; acetic acid; ethyl acetate; 1,1,1,3,3,3-hexamethyl-disilazane; benzene;
In
ethanol; water; toluene;
5: Suzuki-Miyaura cross-coupling;
DOI:10.1002/pola.24792
