C₂₉H₂₇NO₅S₂

Base Information

• Chemical Name: C₂₉H₂₇NO₅S₂
• CAS No.: 1472655-07-4
• Molecular Formula: C₂₉H₂₇NO₅S₂
• Molecular Weight: 533.669
• Mol file: 1472655-07-4.mol

Synonyms:C₂₉H₂₇NO₅S₂

Chemical Property of C₂₉H₂₇NO₅S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₂₇NO₅S₂

There total 6 articles about C₂₉H₂₇NO₅S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

C29H27NO6S (1472655-06-3) → C29H27NO5S2 (1472655-07-4)

Guidance literature:

With Lawessons reagent; In toluene; Reflux;

DOI:10.1021/ja408814g

Reference yield:

5-methylthiophene-2-carboxaldehyde (13679-70-4) → C29H27NO5S2 (1472655-07-4)

Guidance literature:

Multi-step reaction with 6 steps

1.1: pyridine; piperidine / 13 h / 100 °C

2.1: thionyl chloride / chloroform; N,N-dimethyl-formamide / 3 h / Reflux

3.1: sodium azide / 1,4-dioxane; water / 0.5 h / 5 °C

4.1: chloroform; diphenylether / 1 h / 230 °C

5.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 0.67 h / 20 °C / Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

6.1: Lawessons reagent / toluene / Reflux

With piperidine; Lawessons reagent; pyridine; thionyl chloride; sodium azide; N,O-bis-(trimethylsilyl)-acetamide; In 1,4-dioxane; diphenylether; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene; 4.1: |Curtius Rearrangement;

DOI:10.1021/ja408814g

Reference yield:

2-methylthieno[3,2-c]pyridin-4(5H)-one (59207-23-7) → C29H27NO5S2 (1472655-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,O-bis-(trimethylsilyl)-acetamide / dichloromethane / 0.67 h / 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: Lawessons reagent / toluene / Reflux

With Lawessons reagent; N,O-bis-(trimethylsilyl)-acetamide; In dichloromethane; toluene;

DOI:10.1021/ja408814g

upstream raw materials:

2-methylthieno[3,2-c]pyridin-4(5H)-one

C₂₉H₂₇NO₆S

5-methylthiophene-2-carboxaldehyde

(E)-3-(5-Methyl-thiophen-2-yl)-acryloyl chloride