2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide

Base Information

• Chemical Name: 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide
• CAS No.: 1236552-66-1
• Molecular Formula: C₂₁H₂₀N₂O₄
• Molecular Weight: 364.401
• Mol file: 1236552-66-1.mol

Synonyms:2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide

Chemical Property of 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide

There total 1 articles about 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

N-benzyl-2-chloroacetamide (2564-06-9) + 2-(1,3-dioxolan-2-yl)quinolin-8-ol (773093-72-4) → 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide (1236552-66-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.inoche.2010.04.020

Reference yield:

europium(III) nitrate hexahydrate + 2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide (1236552-66-1) → (2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide)trinitratoeuropium(II) (1236552-69-4)

Guidance literature:

In chloroform; ethyl acetate; stoich. amounts of ligand and Eu salt mixed in CHCl3/EtOAc 1:1 v/v;

DOI:10.1016/j.inoche.2010.04.020

upstream raw materials:

N-benzyl-2-chloroacetamide

2-(1,3-dioxolan-2-yl)quinolin-8-ol

Downstream raw materials:

(2-[2-(1,3-dioxolan-2-yl)quinolin-8-yloxy]-N-benzylacetamide)trinitratoeuropium(II)