(2'-methylbiphenyl-2-yl)phenyldiazomethane

Base Information

• Chemical Name: (2'-methylbiphenyl-2-yl)phenyldiazomethane
• CAS No.: 183313-58-8
• Molecular Formula: C₂₀H₁₆N₂
• Molecular Weight: 284.36
• Mol file: 183313-58-8.mol

Synonyms:(2'-methylbiphenyl-2-yl)phenyldiazomethane

Chemical Property of (2'-methylbiphenyl-2-yl)phenyldiazomethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2'-methylbiphenyl-2-yl)phenyldiazomethane

There total 5 articles about (2'-methylbiphenyl-2-yl)phenyldiazomethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(2'-methylbiphenyl-2-yl)phenylmethanone hydrazone (183313-54-4) → (2'-methylbiphenyl-2-yl)phenyldiazomethane (183313-58-8)

Guidance literature:

With potassium hydroxide; sodium sulfate; mercury(II) oxide; In diethyl ether; at 20 ℃;

DOI:10.1002/(SICI)1099-1395(199609)9:9<598::AID-POC825>3.0.CO;2-L

Reference yield:

ortho-tolylmagnesium bromide (932-31-0) → (2'-methylbiphenyl-2-yl)phenyldiazomethane (183313-58-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 80 percent

2: 2. NaOH; 3.) HCl

3: 44 percent

4: 48 percent / hydrazine hydrate / butan-1-ol / 30 h / 110 - 120 °C

5: 50 percent / HgO, Na₂SO₄, 30percent ethanolic KOH / diethyl ether / 20 °C

With hydrogenchloride; potassium hydroxide; sodium hydroxide; hydrazine hydrate; sodium sulfate; mercury(II) oxide; In diethyl ether; butan-1-ol;

DOI:10.1002/(SICI)1099-1395(199609)9:9<598::AID-POC825>3.0.CO;2-L

Reference yield:

2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline (57598-33-1) → (2'-methylbiphenyl-2-yl)phenyldiazomethane (183313-58-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 80 percent

2: 2. NaOH; 3.) HCl

3: 44 percent

4: 48 percent / hydrazine hydrate / butan-1-ol / 30 h / 110 - 120 °C

5: 50 percent / HgO, Na₂SO₄, 30percent ethanolic KOH / diethyl ether / 20 °C

With hydrogenchloride; potassium hydroxide; sodium hydroxide; hydrazine hydrate; sodium sulfate; mercury(II) oxide; In diethyl ether; butan-1-ol;

DOI:10.1002/(SICI)1099-1395(199609)9:9<598::AID-POC825>3.0.CO;2-L

upstream raw materials:

(2'-methylbiphenyl-2-yl)phenylmethanone hydrazone

ortho-tolylmagnesium bromide

2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline

2'-methyl[1,1'-biphenyl]-carboxylic acid

Downstream raw materials:

(2'-methylbiphenyl-2-yl)(phenyl)methanone

2-methyl-2'-[hydroxyl(phenyl)methyl]biphenyl

Refernces