tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane

Base Information

• Chemical Name: tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane
• CAS No.: 138922-13-1
• Molecular Formula: C₃₆H₄₈OSi
• Molecular Weight: 524.862
• Mol file: 138922-13-1.mol

Synonyms:tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane

Chemical Property of tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane

There total 4 articles about tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-methylpent-2-en-4-yn-1-ol (6153-06-6,105-29-3) → tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane (138922-13-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) DIBAH, 2.) I₂ / 1.) hexane, 2.) THF

2: Et₃N, DMAP / CH₂Cl₂

With dmap; iodine; diisobutylaluminium hydride; triethylamine; In dichloromethane;

DOI:10.1016/S0040-4039(00)93574-3

Reference yield:

tert-Butyl-((2E,4E)-5-iodo-3-methyl-penta-2,4-dienyloxy)-diphenyl-silane (138846-07-8) → C28H42 (82848-17-7) + tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane (138922-13-1) + C44H54O2Si2

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)93574-3

Reference yield:

2-[(1’E,3’E)-3’-methyl-4’-iodobuta-1’,3’-dien-1’yl]-1,3,3-trimethylcyclohex-1-ene (138846-06-7) + tert-Butyl-((2E,4E)-5-iodo-3-methyl-penta-2,4-dienyloxy)-diphenyl-silane (138846-07-8) → C28H42 (82848-17-7) + tert-Butyl-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenyloxy]-diphenyl-silane (138922-13-1) + C44H54O2Si2

Guidance literature:

Product distribution; multistep reaction; preparation of a silyl derivative of vitamin A via Pd-catalyzed alkenyl-alkenyl coupling; other metal reagents, other catalyst;

DOI:10.1016/S0040-4039(00)93574-3

upstream raw materials:

2-[(1’E,3’E)-3’-methyl-4’-iodobuta-1’,3’-dien-1’yl]-1,3,3-trimethylcyclohex-1-ene

tert-Butyl-((2E,4E)-5-iodo-3-methyl-penta-2,4-dienyloxy)-diphenyl-silane

(E)-3-methylpent-2-en-4-yn-1-ol

Downstream raw materials:

RETINOL