2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

Base Information

Chemical Name:2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride
CAS No.:910905-39-4
Molecular Formula:C₂₄H₂₅ClN₆O₃*ClH
Molecular Weight:517.415
Hs Code.:

Synonyms:2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

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Chemical Property of 2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

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Technology Process of 2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

There total 1 articles about 2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910905-01-0
(4-(5-aminopyrimidin-2-ylamino)phenyl)(4-methylpiperazin-1-yl)methanone

: 100191-61-5
2-chloro-5-methoxybenzoic acid chloride

: 910905-39-4
2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

Guidance literature:: In tetrahydrofuran; for 18h;

Reference yield: 10.0%

: 910905-39-4
2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride

: 2-chloro-5-hydroxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide

Guidance literature:: 2-chloro-5-methoxy-N-{2-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-pyrimidin-5-yl}-benzamide hydrochloride; With boron tribromide; In dichloromethane; for 43h;

With sodium hydrogencarbonate;