2,3-Dichlorobenzenesulfonyl chloride

Base Information

• Chemical Name: 2,3-Dichlorobenzenesulfonyl chloride
• CAS No.: 82417-45-6
• Molecular Formula: C6H3Cl3O2S
• Molecular Weight: 245.514
• Hs Code.: 29049090
• DSSTox Substance ID: DTXSID101002670
• Wikidata: Q72465492
• Mol file: 82417-45-6.mol

Synonyms:2,3-Dichlorobenzenesulfonyl chloride;82417-45-6;2,3-dichlorobenzene-1-sulfonyl chloride;2,3-DICHLOROBENZENESULPHONYL CHLORIDE;2,3-dichloro-benzenesulfonyl chloride;2,3-DICHLOROBENZENESULPHONYLCHLORIDE;2,3-dichlorobenzenesulfonylchloride;Benzenesulfonyl chloride, dichloro-;2,3-dichlorophenylsulfonyl chloride;72639-48-6;SCHEMBL18457;dichlorobenzenesulfonyl chloride;di-chlorobenzenesulphonyl chloride;DTXSID101002670;2,3-dichlorobenzensulfonyl chloride;2,3-dichlorophenylsulphonyl chloride;2,3-dichlorobenzene-sulphonylchloride;MFCD00051844;2,3-dichloro benzenesulphonyl chloride;2,3-dichlorobenzene-sulphonyl chloride;AKOS001041256;CS-W014637;AM101322;AS-19461;2,3-Dichlorobenzenesulfonyl chloride, 97%;D3568;FT-0609555;EN300-17047;J-506929

Chemical Property of 2,3-Dichlorobenzenesulfonyl chloride

Chemical Property:

• Appearance/Colour: white crystals or crystalline powder
• Vapor Pressure: 0.000275mmHg at 25°C
• Melting Point: 60-64 °C(lit.)
• Refractive Index: 1.581
• Boiling Point: 332.8 °C at 760 mmHg
• Flash Point: 155.1 °C
• PSA: 42.52000
• Density: 1.636 g/cm³
• LogP: 4.00170
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 243.891934
• Heavy Atom Count: 12
• Complexity: 246

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichlorobenzenesulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F; C
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)Cl)S(=O)(=O)Cl

Technology Process of 2,3-Dichlorobenzenesulfonyl chloride

There total 2 articles about 2,3-Dichlorobenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

copper(II) chloride dihydrate + 2,3-dichloroaniline (608-27-5) → dichlorobenzenesulfonyl chloride (82417-45-6)

Guidance literature:

With hydrogenchloride; sulfur dioxide; sodium nitrite; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water; acetic acid;

Reference yield:

→ dichlorobenzenesulfonyl chloride (82417-45-6)

Guidance literature:

Reference yield: 97.0%

(3R)-3-amino-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester hydrochloride (1246509-66-9) + dichlorobenzenesulfonyl chloride (82417-45-6) → (R)-methyl 3-(2,3-dichlorophenylsulfonamido)-2,3-dihydro-1H-indene-5-carboxylate (1246506-37-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;

upstream raw materials:

2,3-dichloroaniline

Downstream raw materials:

2,3-dichlorobenzenesulfonic acid 3-hydroxy-5-methylphenyl ester

2,3-dichlorobenzenesulfonic acid 3-ethyl-5-hydroxyphenyl ester

2,3-dichlorobenzenesulfonic acid 3-hydroxyphenyl ester

7-amino-6-[4-(2,3-dichloro-benzenesulfonylamino)-phenyl]-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester