2,6-Dichloro-3-iodopyridine

Base Information

Chemical Name:2,6-Dichloro-3-iodopyridine
CAS No.:148493-37-2
Molecular Formula:C5H2Cl2IN
Molecular Weight:273.888
Hs Code.:2933399090
European Community (EC) Number:640-726-0
DSSTox Substance ID:DTXSID10371076
Nikkaji Number:J1.537.714C
Wikidata:Q72466568
Mol file:148493-37-2.mol

Synonyms:2,6-Dichloro-3-iodopyridine;148493-37-2;Pyridine, 2,6-dichloro-3-iodo-;MFCD03094686;2,6-dichloro-3-iodo-pyridine;SCHEMBL1344323;DTXSID10371076;DPCQIHCGMIPSQV-UHFFFAOYSA-N;BCP22127;BBL101716;GEO-03682;STL555513;2,6-Dichloro-3-iodopyridine, 97%;2 pound not6-Dichloro-3-Iodopyridine;AKOS007930390;AC-9481;AM62365;CS-W010089;GS-6733;SY016472;A3253;D5061;FT-0643422;EN300-71557;W-205677

Suppliers and Price of 2,6-Dichloro-3-iodopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Dichloro-3-iodopyridine
500mg
$ 60.00

TRC
2,6-Dichloro-3-iodopyridine
2.5g
$ 75.00

TCI Chemical
2,6-Dichloro-3-iodopyridine >98.0%(GC)
5g
$ 254.00

TCI Chemical
2,6-Dichloro-3-iodopyridine >98.0%(GC)
1g
$ 63.00

SynQuest Laboratories
2,6-Dichloro-3-iodopyridine
5 g
$ 31.00

SynQuest Laboratories
2,6-Dichloro-3-iodopyridine
1 g
$ 16.00

Sigma-Aldrich
2,6-Dichloro-3-iodopyridine 97%
1g
$ 77.00

Matrix Scientific
2,6-Dichloro-3-iodopyridine 98%
5g
$ 47.00

Matrix Scientific
2,6-Dichloro-3-iodopyridine 98%
100g
$ 235.00

Matrix Scientific
2,6-Dichloro-3-iodopyridine 98%
25g
$ 79.00

Total 91 raw suppliers

Chemical Property of 2,6-Dichloro-3-iodopyridine

Chemical Property:

Appearance/Colour:Light yellow powder
Vapor Pressure:0.00279mmHg at 25°C
Melting Point:74-79℃
Refractive Index:1.652
Boiling Point:294.8 °C at 760 mmHg
PKA:-3.87±0.10(Predicted)
Flash Point:132.1 °C
PSA：12.89000
Density:2.129 g/cm³
LogP:2.99300
Storage Temp.:2-8°C
Sensitive.:Light Sensitive
Water Solubility.:Slightly soluble in water.
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:272.86090
Heavy Atom Count:9
Complexity:101

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dichloro-3-iodopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22-37/38-41
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC(=C1I)Cl)Cl
Uses It is used as pharmaceutical raw material and intermediate.

Technology Process of 2,6-Dichloro-3-iodopyridine

There total 3 articles about 2,6-Dichloro-3-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 2402-78-0
2,6-dichloropyridine

: 148493-37-2
2,6-dichloro-3-iodo-pyridine

Guidance literature:: 2,6-dichloropyridine; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -75 ℃; for 2h;

With iodine; In tetrahydrofuran;
DOI:10.1002/1099-0690(200104)2001:7<1371::AID-EJOC1371>3.0.CO;2-E

Reference yield: 64.0%

: 2402-78-0
2,6-dichloropyridine

: 98027-84-0
2,6-dichloro-4-iodopyridine

: 148493-37-2
2,6-dichloro-3-iodo-pyridine

Guidance literature:: 2,6-dichloropyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃; for 0.75h;

With iodine; In tetrahydrofuran; hexane; at -75 ℃; for 0.25h;
DOI:10.1021/jo047962z

Reference yield:

: 2402-78-0
2,6-dichloropyridine

: 98027-84-0
2,6-dichloro-4-iodopyridine

: 1182718-72-4
2,6-dichloro-3,4-diiodopyridine

: 1353056-37-7
2,6-dichloro-3,5-diiodopyridine

: 148493-37-2
2,6-dichloro-3-iodo-pyridine

Guidance literature:: 2,6-dichloropyridine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; ZnCl₂-N,N,N’,N’-tetramethylethylenediamine; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

With iodine; In tetrahydrofuran; regioselective reaction; Inert atmosphere;
DOI:10.1002/chem.201101993