(2,4-Difluorophenyl)(piperidin-4-yl)methanone

Base Information

Chemical Name:(2,4-Difluorophenyl)(piperidin-4-yl)methanone
CAS No.:84162-86-7
Molecular Formula:C12H13 F2 N O
Molecular Weight:225.238
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70517438
Nikkaji Number:J2.766.165C
Wikidata:Q72463991
Mol file:84162-86-7.mol

Synonyms:84162-86-7;(2,4-Difluorophenyl)(piperidin-4-yl)methanone;1-(2',4'-Difluorophenyl)-1-(4-piperidinyl) methanone;(2,4-Difluoro-phenyl)-piperidin-4-yl-methanone;(2,4-difluorophenyl)-piperidin-4-ylmethanone;4-(2,4-difluorobenzoyl)piperidine;2,4-Difluorophenyl-4-piperidyl ketone;Oprea1_310882;SCHEMBL4672830;DTXSID70517438;WQJPGQDCLBMXMH-UHFFFAOYSA-N;MFCD08458383;AKOS000163824;SB38949;2,4-difluorophenyl piperidin-4-yl ketone;AC-15752;AS-47179;AM20120492;CS-0456128;FT-0651255;(2,4-difluorophenyl)(4-piperidinyl)methanone;F12476;Methanone, (2,4-difluorophenyl)-4-piperidinyl-;A840725;1-(2,4-Difluorophenyl)-1-(4-piperidinyl)methanone;1-(2' pound not4'-difluorophenyl)-1-(4-piperidinyl)methanone;(2,4-difluorophenyl)-(4-piperidyl)methanone

Suppliers and Price of (2,4-Difluorophenyl)(piperidin-4-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-(2,4-Difluorobenzoyl)piperidine 96%
1 g
$ 46.00

SynQuest Laboratories
4-(2,4-Difluorobenzoyl)piperidine 96%
5 g
$ 139.00

J&W Pharmlab
(2,4-Difluoro-phenyl)-piperidin-4-yl-methanone 97%
100g
$ 120.00

J&W Pharmlab
(2,4-Difluoro-phenyl)-piperidin-4-yl-methanone 97%
500g
$ 480.00

Crysdot
(2,4-Difluorophenyl)(piperidin-4-yl)methanone 95+%
5g
$ 823.00

Chemenu
1-(2'',4''-Difluorophenyl)-1-(4-piperidinyl)methanone 95%
5g
$ 777.00

American Custom Chemicals Corporation
1-(2',4'-DIFLUOROPHENYL)-1-[4-PIPERIDINYL] METHANONE 95.00%
5G
$ 1016.28

Alichem
(2,4-Difluorophenyl)(piperidin-4-yl)methanone
1g
$ 400.00

Total 23 raw suppliers

Chemical Property of (2,4-Difluorophenyl)(piperidin-4-yl)methanone

Chemical Property:

Vapor Pressure:0.000366mmHg at 25°C
Melting Point:547-548 °C
Boiling Point:318.2oC at 760 mmHg
PKA:9.62±0.10(Predicted)
Flash Point:146.3oC
PSA：29.10000
Density:1.198g/cm3
LogP:2.47590
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:225.09652036
Heavy Atom Count:16
Complexity:253

Purity/Quality:

97% ^*data from raw suppliers

4-(2,4-Difluorobenzoyl)piperidine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)C2=C(C=C(C=C2)F)F

Technology Process of (2,4-Difluorophenyl)(piperidin-4-yl)methanone

There total 1 articles about (2,4-Difluorophenyl)(piperidin-4-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84162-86-7
(2,4-difluorophenyl)(4-piperidinyl)methanone

Guidance literature:

Reference yield: 84.0%

: 5-Methanesulfonyl-2-(2,2,3,3,3-pentafluoro-propoxy)-benzoic acid

: 84162-86-7
(2,4-difluorophenyl)(4-piperidinyl)methanone

: (4-(2,4-difluorobenzoyl)piperidin-1-yl)(5-(methylsulfonyl)-2-(2,2,3,3,3-pentafluoropropoxy)phenyl)methanone

Guidance literature:: 5-Methanesulfonyl-2-(2,2,3,3,3-pentafluoro-propoxy)-benzoic acid; With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 0.5h;

(2,4-difluorophenyl)(4-piperidinyl)methanone; With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1039/c5ra04714e

Reference yield: 80.0%

: 84162-86-7
(2,4-difluorophenyl)(4-piperidinyl)methanone

: C₁₂H₁₅NO₅S

: 4-(cyclopropylmethoxy)-3-(4-(2,4-difluorobenzoyl)piperidine-1-carbonyl)-N-methylbenzenesulfonamide

Guidance literature:: C₁₂H₁₅NO₅S; With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 0.5h;

(2,4-difluorophenyl)(4-piperidinyl)methanone; With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1039/c5ra04714e