(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate

Base Information

• Chemical Name: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate
• CAS No.: 1231169-97-3
• Molecular Formula: C₂₉H₄₁NO₂
• Molecular Weight: 435.65

Synonyms:(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate

Chemical Property of (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate

Chemical Property:

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Technology Process of (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate

There total 1 articles about (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

N-(3-methylbenzylidene)-1-phenylmethanamine + (-)-menthyl butyrate (6070-14-0,80656-95-7,92319-43-2,115114-96-0,141553-00-6,68366-64-3) → (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R)-2-[(R)-1-benzylamino-1-(3-methylphenyl)methyl]butanoate (1231169-97-3)

Guidance literature:

With titanium tetrachloride; triethylamine; In dichloromethane; at -45 ℃; for 6.66667h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetasy.2010.02.010

upstream raw materials:

(-)-menthyl butyrate

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