2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside

Base Information

• Chemical Name: 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside
• CAS No.: 870136-62-2
• Molecular Formula: C₆₃H₅₃N₃O₁₈
• Molecular Weight: 1140.12
• Mol file: 870136-62-2.mol

Synonyms:2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside

Chemical Property of 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside

There total 2 articles about 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-chloroethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside (870136-61-1) → 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside (870136-62-2)

Guidance literature:

With sodium azide; 18-crown-6 ether; In N,N-dimethyl-formamide; at 70 ℃; for 36h;

DOI:10.1016/j.bmc.2005.06.036

Reference yield:

2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1→4)-2,3,6-tri-O-benzoyl-α-D-glucopyranosyl bromide (61198-91-2) → 2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside (870136-62-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / silver triflate; molecular sieves 4 Angstroem / CH₂Cl₂ / 2 h / 0 °C

2: 90 percent / sodium azide; 18-crown-6 / dimethylformamide / 36 h / 70 °C

With sodium azide; 18-crown-6 ether; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2005.06.036

Reference yield: 91.0%

2-azidoethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside (870136-62-2) → 2-azidoethyl β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside (230286-11-0)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 16h;

DOI:10.1016/j.bmc.2005.06.036

upstream raw materials:

2-chloroethyl (2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzoyl-β-D-glucopyranoside

2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1→4)-2,3,6-tri-O-benzoyl-α-D-glucopyranosyl bromide

Downstream raw materials:

2-azidoethyl β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside