Technology Process of C12H14N4O2
There total 6 articles about C12H14N4O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium azide;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/ejoc.201001375
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: thionyl chloride / dichloromethane / 1 h / Inert atmosphere; Reflux
2.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
4.2: 1 h / 20 °C / Inert atmosphere
5.1: sodium azide / N,N-dimethyl-formamide / 12 h / 80 °C / Inert atmosphere
With
lithium aluminium tetrahydride; thionyl chloride; sodium azide; potassium tert-butylate; sodium hydride;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/ejoc.201001375
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
3.1: sodium azide / N,N-dimethyl-formamide / 12 h / 80 °C / Inert atmosphere
With
lithium aluminium tetrahydride; sodium azide; sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/ejoc.201001375
