methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate

Base Information

• Chemical Name: methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate
• CAS No.: 862855-96-7
• Molecular Formula: C₃₃H₃₆N₄O₅
• Molecular Weight: 568.673
• Mol file: 862855-96-7.mol

Synonyms:methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate

Chemical Property of methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate

There total 1 articles about methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (3R)-3-(4-{[5-(4-amino-3-methoxyphenyl)-2,4-dimethyl-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate (862855-95-6) + 2-tolyl isocyanate (614-68-6) → methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate (862855-96-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 96h;

Reference yield:

methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate (862855-96-7) → (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoic acid

Guidance literature:

methyl (3R)-3-(4-{[2,4-dimethyl-5-[3-methoxy-4-({[(2-methylphenyl)amino]carbonyl}amino)phenyl]-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 2.5h;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃;

upstream raw materials:

methyl (3R)-3-(4-{[5-(4-amino-3-methoxyphenyl)-2,4-dimethyl-6-oxo-1(6H)-pyrimidinyl]methyl}phenyl)butanoate

2-tolyl isocyanate