(R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate

Base Information

Chemical Name:(R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate
CAS No.:363191-25-7
Molecular Formula:C9H18N2O4
Molecular Weight:218.25
Hs Code.:2924199090
DSSTox Substance ID:DTXSID90426957
Wikidata:Q72469972
Mol file:363191-25-7.mol

Synonyms:363191-25-7;H-D-Dap(Boc)-Ome;(R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate;3-[[(1,1-Dimethylethoxy)carbonyl]amino]-D-alanine methyl ester;3-(N-BOC-Amino)-D-alanine methyl ester;methyl (2R)-2-amino-3-{[(tert-butoxy)carbonyl]amino}propanoate;methyl (2R)-2-amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate;H-D-DAP(BOC)-OME HCL;SCHEMBL584353;DTXSID90426957;MFCD11100944;AKOS016844255;AC-6365;DS-5994;CS-0031339;EN300-7187815;(R)-Methyl 2-amino-3-((t-butoxycarbonyl)amino)propanoate;Methyl (R)-2-amino-3-(tert-butoxycarbonylamino)propanoate;3-(1,1-Dimethyl ethoxy)carbonylamino-D-alanine methyl ester;Methyl (2R)-2-amino-3-[(tert-butoxycarbonyl)amino]propanoate, AldrichCPR

Suppliers and Price of (R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(N-Boc-Amino)-D-alanineMethylEster
1g
$ 350.00

TRC
3-(N-Boc-Amino)-D-alanineMethylEster
100mg
$ 85.00

TRC
3-(N-Boc-Amino)-D-alanineMethylEster
250mg
$ 160.00

Iris Biotech GmbH
H-D-Dap(Boc)-OMe*HCl
500 mg
$ 121.50

Crysdot
H-D-Dap(Boc)-OMe 97%
5g
$ 387.00

ChemPep
H-D-Dap(Boc)-OMe?HCl
5g
$ 725.00

ChemPep
H-D-Dap(Boc)-OMe?HCl
1g
$ 250.00

Chem-Impex
D-α,β-Diaminopropionicacid(Boc)methylesterhydrochloride,≥99%(HPLC) ≥99%(HPLC)
250MG
$ 58.24

Chem-Impex
D-α,β-Diaminopropionicacid(Boc)methylesterhydrochloride,≥99%(HPLC) ≥99%(HPLC)
1G
$ 186.37

Chemenu
(R)-Methyl2-amino-3-((tert-butoxycarbonyl)amino)propanoate 95%
1g
$ 222.00

Total 28 raw suppliers

Chemical Property of (R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate

Chemical Property:

Vapor Pressure:0.000227mmHg at 25°C
Refractive Index:1.463
Boiling Point:325.676 °C at 760 mmHg
PKA:11.95±0.46(Predicted)
Flash Point:150.764 °C
PSA：90.65000
Density:1.108 g/cm³
LogP:1.90460
Storage Temp.:2-8°C
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:218.12665706
Heavy Atom Count:15
Complexity:235

Purity/Quality:

97% ^*data from raw suppliers

3-(N-Boc-Amino)-D-alanineMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(C(=O)OC)N
Isomeric SMILES:CC(C)(C)OC(=O)NC[C@H](C(=O)OC)N

Technology Process of (R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate

There total 2 articles about (R)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96136-12-8
2-benzyloxycarbonylamino-3-tert-butoxycarbonylamino-propionic acid methyl ester

: 363191-25-7,161972-25-4
methyl N³-(tert-butyloxycarbonyl)-(R)-2,3-diaminopropinate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 4h; Ambient temperature;
DOI:10.1021/jm980722p

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 363191-25-7,161972-25-4
methyl N³-(tert-butyloxycarbonyl)-(R)-2,3-diaminopropinate

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaHCO₃ / CH₂Cl₂ / 4 h / Ambient temperature

2: H₂ / 10 percent Pd/C / ethanol / 4 h / Ambient temperature

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm980722p

Reference yield:

: 1436426-21-9
4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)aniline

: 363191-25-7,161972-25-4
methyl N³-(tert-butyloxycarbonyl)-(R)-2,3-diaminopropinate

: 477199-77-2
4-(bromomethyl)-2-fluorobenzoic acid

: C₃₀H₃₈ClF₄N₅O₅

Guidance literature:: 4-(bromomethyl)-2-fluorobenzoic acid; With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h;

4-chloro-2-(4-(3,3,3-trifluoropropyl)piperazin-1-yl)aniline; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.5h;

methyl N³-(tert-butyloxycarbonyl)-(R)-2,3-diaminopropinate; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 80 ℃; for 1h;